- Jackie Coogan
- Tom Sawyer
- Junior Durkin
- Huckleberry Finn
- Mitzi Green
- Becky Thatcher
- Lucien Littlefield
- Schoolteacher
- Tully Marshall
- Muff Potter
- Clara Blandick
- Aunt Polly
- Mary Jane Irving
- Mary Sawyer
- Ethel Wales
- Mrs. Harper
- Dick Winslow
- Joe Harper
- Jackie Searl
- Sidney Sawyer
- Jane Darwell
- Widow Douglas
- Charles Stevens
- Injun Joe
- Charles Sellon
- Minister
- Lon Poff
- Judge Thatcher
- Dannie Mac Grant
- Young Boy
- Carmencita Johnson
- Little Girl
