- Mary Carlisle
- Marjorie Rogers
- Lloyd Nolan
- Bob Anders
- Roscoe Karns
- Tom Benson aka Tommy Logan
- Buster Crabbe
- John A. 'Red' Deegan
- J. Carrol Naish
- Joseph Valkus
- Evelyn Brent
- Rena Terry
- Anthony Quinn
- Marty
- Benny Baker
- Scotty
- Harvey Stephens
- Chief Agent Jason Baardue
- Irving Bacon
- Sam
- Gertrude Short
- 'Boots' Milburn
- Archie Twitchell
- Hensler
- Barlowe Borland
- Blacky
- Pierre Watkin
- George Murkil
- Richard E. Allen
- Police Lieutenant
- Stanley Andrews
- Police Sergeant
- Frank Austin
- Gus, Diner Manager
- Wade Boteler
- Pete
- Wally Dean
- First Trucking Magnate
- Paula DeCardo
- Tip-Off Girl
- Vic Demourelle
- Truck Driver
- Frank Fanning
- Police Officer
- Carl Faulkner
- Detective in Car
- Harry Fleischmann
- Cop
- John Hart
- Truck Driver
- Oscar 'Dutch' Hendrian
- Dutch, a Highjacker
- Al Herman
- Proprietor
- Barbara Jackson
- Nurse
- Lola Jensen
- Tip-Off Girl
- Willard Kent
- Cop
- Stanley King
- Truck Driver
- Ethan Laidlaw
- Truck Driver
- Laurie Lane
- Waitress
- Wally Maher
- Gus, Garage Attendant
- Joyce Mathews
- Tessie
- Frank Mayo
- Third Trucking Magnate
- Harold Miller
- Businessman
- Frank Mills
- Night Club Patron
- Field Norton
- Second Trucking Magnate
- John Patterson
- Jim
- Jack Pennick
- Truck Driver
- Stanley Price
- Louie
- Margaret Randall
- Waitress
- Ruth Rogers
- Waitress
- Dick Rush
- Detective in Car
- Harry Templeton
- Truck Driver
- Cheryl Walker
- Waitress
- Phil Warren
- Steve
- Marion Weldon
- Tip-Off Girl / Night Club Patron (uncredited)
- Pat West
- Proprietor
- Gloria Williams
- Tip-Off Girl
