- Adam Sandler
- Tommy
- Terry Crews
- Chico
- Jorge Garcia
- Herm
- Taylor Lautner
- Lil Pete
- Rob Schneider
- Ramon
- Luke Wilson
- Danny
- Will Forte
- Will Patch
- Steve Zahn
- Clem
- Harvey Keitel
- Smiley
- Nick Nolte
- Frank Stockburn
- Jon Lovitz
- Grant
- Whitney Cummings
- Susannah
- David Spade
- General George Custer
- Danny Trejo
- Cicero
- Nick Swardson
- Nelly Patch
- Blake Shelton
- Wyatt Earp
- Vanilla Ice
- Mark Twain
- Julia Jones
- Smoking Fox
- Saginaw Grant
- Screaming Eagle
- Lavell Crawford
- Gus Patch
- Steve Buscemi
- Doc Griffin
- John Turturro
- Abner Doubleday
- Chris Parnell
- Bank Manager
- Dana Goodman
- Beaver Breath
- Jared Sandler
- Babyface Patch
- Jackie Sandler
- Never Wears Bra
- Norm MacDonald
- Nugget Customer
- Dan Patrick
- Abe Lincoln
- Chris Kattan
- John Wilkes Booth
- Blake Clark
- Gulch Sheriiff
- Katalina Parrish
- Sheriff's Wife
- Julia Vera
- Esmerelda
- Chris Titone
- Beefer
- Tim Herlihy
- Nugget Bartender
- Sadie Sandler
- Dancing Kid #1
- Sunny Sandler
- Dancing Kid #2
- Kenneth Ruthardt
- Raging Bear
- J.D. Donaruma
- JD
- Jonathan Loughran
- Rifleman
- Dan Bulla
- Dr. Chubb
- Kevin Grady
- Nugget Bouncer #1
- King Orba
- Nugget Bouncer #2
- Kimo Keoke
- Short Stop
- James Ning
- QI
- Sarah Minnich
- Woman Bank Customer
- Ryan Happy
- Train Robber #1
- Derek Lacasa
- Train Robber #2
- Tina Parker
- Mary Todd Lincoln
- Stephen Eiland
- Fainting Man
- Henry Steckman
- Young Tommy
- Catharine E. Jones
- Betty Dunson
- Ruben Rivera Laguna
- Young Cicero
- David Manzanares
- Cicero Gang Member
- Alex Knight
- Ford's Theater Performer #1
- Lauren Poole
- Ford's Theater Performer #2
- Patrick Gozur
- Ford's Theater Performer #3
- Fernando Fresquez
- Ford's Theater Performer #4
- Robin Leach
- Herm
- Ricardo Andres
- Sober Bar Patron
- Rick Anglada
- Apache Warrior
- Richard Beal
- Town Cowboy
- Todd Bethke
- Citizen of Roscoe Plains
- Derek Blakeney
- Blacksmith
- Paul Caster
- Angry Townsman
- Warren M. Christopher
- Gallows Deputy
- Jetto Dorsainville
- Rattlers Gulch Man
- Melissa-Lou Ellis
- Saloon Girl
- John Farley
- Roscoe
- Madison Fogle
- School Girl
- Corinne Fox
- Soiled Dove Saloon Girl
- Christopher W. Garcia
- Towns Boy
- Steffen Diem Garcia
- Drifter
- John Gibbs
- Apache Warrior
- Alan Humphrey
- Cowboy
- Bill Jones
- Wheel of Fortune Dealer
- Chelsea Arielle Kibbee
- Saloon Girl
- Bob Knowlton
- Townsman
- James E. Lane
- Gambling Cowboy-Wheel of Fortune
- Rodger Larance
- Townsman
- Ricky Lee
- Medicine Man
- Kearon Lehman
- Guard
- Justin Lotz
- Bar Patron at Golden Nugget Saloon
- David Loving
- Banker
- Jameson Macmillan
- Cowboy / Townsman (uncredited)
- Meggie Maddock
- Nugget Prostitute
- Tristan Manyhorses
- Special ability rider / Native village (uncredited)
- Max Manzanares
- Townboy
- Julianne Medina
- Towns Girl
- Crystal Miller
- Saloon Girl
- Victoria L. Moya
- Villager
- Natasha Nazario
- Nugget Prostitute
- Denny O'Connor
- Dancing Drunk
- Martin Palmer
- Gambler
- Maximus A. Passeno
- Schoolyard Boy
- Anastasia Peralta
- Townperson
- Michael Neal Powell
- Roscoe 'Doc' / Gulch Gambler (uncredited)
- Burton Ritchie
- Townsman
- Gonzalo Robles
- Guard
- Paul Sado
- Stumbles Patch
- Caroline Schademan
- Townswoman
- Natalie Jane Shields
- Townsperson
- J. Nathan Simmons
- Citizen of Rattler's Gulch
- Michael E. Stogner
- Citizen of Rattler's Gulch
- Vanessa Torres
- Sexy Bar Girl
- Julia Lea Wolov
- School Marm
