- George C. Scott
- Dr. Herbert Bock
- Diana Rigg
- Barbara Drummond
- Barnard Hughes
- Drummond / Dr. Mallory
- Richard Dysart
- Dr. Welbeck
- Stephen Elliott
- Dr. Sundstrom
- Donald Harron
- Milton Mead
- Andrew Duncan
- William Mead
- Nancy Marchand
- Mrs. Christie
- Jordan Charney
- Hitchcock
- Roberts Blossom
- Guernsey
- Lenny Baker
- Dr. Schaefer
- Richard Hamilton
- Dr. Ronald Casey
- Arthur Junaluska
- Mr. Blacktree
- Kate Harrington
- Nurse Dunne
- Katherine Helmond
- Marilyn Mead
- David Hooks
- Dr. Einhorn
- Frances Sternhagen
- Mrs. Cushing
- Robert Walden
- Dr. Brubaker
- William Perlow
- Cardiac Arrest Doctor
- Bette Henritze
- Operating Room Nurse
- Rehn Scofield
- Dr. Spezio
- Dora Weissman
- Lady in the Hospital
- Carolyn Krigbaum
- Dr. Bock's Secretary
- Robert Anthony
- Dr. Elroy Ives
- Leigh Beery
- Mead's Secretary
- Cynthia Belgrave
- Nurse Reardon
- Norman Berns
- Dr. Biegelman
- Charles Bershatsky
- Boswell
- Jacqueline Brookes
- Dr. Immelman
- Lonnie Burr
- Intern
- Stockard Channing
- E.R. Nurse
- Paddy Chayefsky
- Opening Narrator
- Alex Colon
- Young Lord
- Matthew Cowles
- Intern Chandler
- Reid Cruickshanks
- Chief Engineer
- Anita Dangler
- Paranoid Lady
- Jean David
- Stephanie McGuire
- Lorrie Davis
- Nurse Divine
- Dawn Powell Dell
- Hospital Visitor
- Dennis Dugan
- E.R. Doctor
- Eddie Epstein
- Resident
- Milton Earl Forrest
- Militant Leader
- George Garcia
- Militant Leader
- Julie Garfield
- Nurse Perez
- Richard Goode
- Dr. Sutcliffe
- Nat Grant
- Black Panther
- Sarina C. Grant
- Nurse X
- Christopher Guest
- Resident
- Nat Horne
- Patient
- Bette Howard
- Young Mother
- Tresa Hughes
- Mrs. Donovan
- Paul Jott
- Administrative Resident
- Bruce Kornbluth
- Young Activist Doctor
- Bill Lazarus
- Police Captain
- Mary Rio Lewis
- Lady
- Paul Mace
- Intern Ambler
- Nancy MacKay
- Sheilah
- Marja Maitland
- Nurse's Aide
- Tony Major
- Ambulance Attendant
- Shawn McAllister
- Medical Intern
- Ruth Attaway Morrison
- Circulating Nurse
- Joy Nicholson
- Sundstrom's Secretary
- Bob O'Connell
- Policeman
- Angie Ortega
- Nurse Teresa Campanella
- Janet Paul
- Emergency Room Receptionist
- Lou Polan
- Dr. Lagerman
- Paul B. Price
- Nameless Man
- Janet Sarno
- Nurse Rivers
- Sab Shimono
- Operating Room Staff
- Marilyn Sokol
- Lady Lib.
- Tom Spratley
- Mitgang
- John Tremaine
- Doctor
- Tracey Walter
- Man in Crowd
- Paul Whaley
- Hospital Spokesman
- Gena Wheeler
- Holding Nurse
- Lydia Wilen
- Emergency Nurse
