- Pearl White
- Elaine Dodge
- Arnold Daly
- Detective Craig Kennedy
- Creighton Hale
- Walter Jameson (Ep. 1, 2, 3, 6)
- Raymond Owens
- Walter Jameson (Ep. 4-14)
- Sheldon Lewis
- Perry Bennett / The Clutching Hand
- Edwin Arden
- Wu Fang
- Leroy Baker
- The Butler
- Bessie Wharton
- Aunt Josephine - Mrs. Dodge
- Riley Hatch
- President Dodge
- Robin H. Townley
- Limpy Red
- Floyd Buckley
- Michael
- Lionel Barrymore
- Undetermined Role
- M.W. Rale
- Wong Lang Sin
- Howard Cody
- Undetermined Role
- Paul Panzer
- Undetermined Role
