- Andy Richter
- Self - Host
- Carlos Alazraqui
- Self
- Dave Allen
- The Naked Trucker
- Barenaked Ladies
- Themselves - Performer
- Lewis Black
- Self
- Dave Chappelle
- Self
- Stephen Colbert
- Self
- Rob Corddry
- Self
- David Cross
- Self - Presenter
- Rodney Dangerfield
- Self
- Andy Dick
- Self
- Rachel Dratch
- Self
- Russell Duncan
- Self - Comedian
- Susie Essman
- Self
- Will Ferrell
- Self
- Dave Foley
- Self - Presenter
- Marla Gibbs
- Self
- Skyler Gisondo
- Justin
- Gilbert Gottfried
- Self - Presenter
- Kathy Griffin
- Self
- Luis Guzmán
- Self - Presenter
- Alyson Hannigan
- Self
- Ed Helms
- Self
- Christy Hemme
- Self - Presenter
- David Koechner
- T-Bones
- Eugene Levy
- Self
- Mitch Lewis
- Self - Announcer
- Liam Lynch
- Self - Performer
- Cheech Marin
- Self - Presenter
- Christopher Masterson
- Self - Presenter
- Danny Masterson
- Self - Presenter
- Wendi McLendon-Covey
- Self
- Jerry Minor
- Self - Performer
- 'Big' LeRoy Mobley
- Security Guard
- Niecy Nash
- Self
- Bob Odenkirk
- Self - Presenter
- Joe Pantoliano
- Self
- Dat Phan
- Self
- Colin Quinn
- Self - Presenter
- Sara Rue
- Self
- Adam Sandler
- Self - Presenter
- Tony Shalhoub
- Self - Presenter
- Robert Smigel
- Triumph the Insult Comic Dog
- Aries Spears
- Self
- Doug Stanhope
- Self
- Jon Stewart
- Self
- Nick Swardson
- Self
- Wanda Sykes
- Self - Presenter
- Jeffrey Tambor
- Self
- Scott Thompson
- Self
- Paul F. Tompkins
- "Must Be Nice" Guy
- Fred Willard
- Self - Presenter
- Harland Williams
- Self - Presenter
- Jim Creeggan
- Self - Barenaked Ladies
- Kevin Hearn
- Self - Barenaked Ladies
- Steven Page
- Self - Barenaked Ladies
- Ed Robertson
- Self - Barenaked Ladies
- Tyler Stewart
- Self - Barenaked Ladies
