- James Cagney
- Steve Collins
- Bette Davis
- Joan Winfield
- Stuart Erwin
- Tommy Keenan
- Eugene Pallette
- Lucius K. Winfield
- Jack Carson
- Allen Brice
- George Tobias
- Peewee
- Harry Davenport
- Pop Tolliver
- William Frawley
- Sheriff McGee
- Edward Brophy
- Hinkle
- Harry Holman
- Judge Sobler
- Chick Chandler
- First Reporter
- Douglas Kennedy
- Second Reporter
- Herbert Anderson
- 3rd Reporter
- William Newell
- McGee's Pilot
- William Hopper
- Keenan's Pilot
- Sol Gorss
- Reporters' Pilot
- Jean Ames
- Mabel - Hatcheck Girl
- Peter Ashley
- Reporter in Amarillo
- Mary Brodel
- KFWB Operator #2
- Ralph Brooks
- Radio Station Man in Booth
- Bob Brossard
- Junior Flight Officer
- George Campeau
- Reporter in Amarillo
- Lucia Carroll
- Steve's Airplane Date
- Eddy Chandler
- Policeman - Driver of Car #64
- Richard Clayton
- Newsboy
- Garrett Craig
- Flight Officer
- Oliver Cross
- Embassy Club Patron
- Jimmy the Crow
- Pop Tolliver's Crow
- George Davis
- Embassy Club Waiter
- Peggy Diggins
- KFWB Operator #1
- Tom Ferrandini
- Embassy Club Patron
- James Flavin
- Interrogating Detective
- William Forrest
- Asst. Dist. Atty. Edwards
- John Gallaudet
- Winfield's First Pilot
- Paul Gustine
- Embassy Club Patron
- Creighton Hale
- Reporter #5
- Sam Harris
- Embassy Club Patron
- Sam Hayes
- Announcer
- Charles Anthony Hughes
- Policeman in Car #64
- Olaf Hytten
- Winfield's Valet
- Reid Kilpatrick
- Announcer
- Max Linder
- Embassy Club Doorman
- Paul Mantz
- Winfield's Second Pilot
- Alphonse Martell
- Embassy Club Headwaiter
- Frank Mayo
- Reporter / Photographer #4 (uncredited)
- Jack Mower
- Reporter / Photographer #6 (uncredited)
- Lee Phelps
- Policeman at Interrogation
- The Rogers Dancers
- Dance Trio at Embassy Club
- Loretta Russell
- Embassy Club Patron
- Cliff Saum
- Airport Mechanic
- Garland Smith
- Newsboy
- Charles Sullivan
- Charlie - Ambulance Driver
- Lester Towne
- Newsboy
- Richard Travis
- Airline Dispatcher
- Claude Wisberg
- Newsboy
- Victor Zimmerman
- Aeronautics Division Official
