- Paula Patton
- Self
- Amanda Seyfried
- Self - Presenter
- Ben Stiller
- Self - Presenter
- Zoë Kravitz
- Self
- Demi Moore
- Self - Presenter
- Zoe Saldana
- Self - Presenter / Neytiri
- Colin Farrell
- Self - Presenter
- Kate Winslet
- Self - Presenter
- Macaulay Culkin
- Self - John Hughes Tribute
- Tom Hanks
- Self - Presenter
- Ryan Reynolds
- Self - Presenter
- Keanu Reeves
- Self - Presenter
- Julianne Moore
- Self - Presenter
- Jake Gyllenhaal
- Self - Presenter
- Gerard Butler
- Self - Presenter
- Rachel McAdams
- Self - Presenter
- Quentin Tarantino
- Self - Nominee & Presenter
- Matt Damon
- Self - Nominee & Presenter
- Anna Kendrick
- Self - Nominee & Presenter
- Jason Bateman
- Self - Presenter
- Jeff Bridges
- Self - Winner & Presenter
- Dakota Fanning
- Coraline
- Charlize Theron
- Self - Presenter
- Morgan Freeman
- Self - Nominee
- Elizabeth Banks
- Self - Hostess: Scientific & Technical Awards
- Cameron Diaz
- Self - Presenter
- Kathy Bates
- Self - Presenter
- Sandra Bullock
- Self - Winner & Presenter
- Robert Downey Jr.
- Self - Presenter
- Kristen Stewart
- Self - Presenter
- Robin Williams
- Self - Presenter
- Stanley Tucci
- Self - Nominee & Presenter
- John Travolta
- Self - Presenter
- George Clooney
- Self - Nominee / Mr. Fox
- Bradley Cooper
- Self - Presenter
- Sigourney Weaver
- Self - Presenter
- Woody Harrelson
- Self - Nominee
- Diane Kruger
- Self
- Zac Efron
- Self - Presenter
- Michelle Pfeiffer
- Self - Presenter
- David Fincher
- Self (segment "Where People and Ideas Begin")
- John Hughes
- Self - Special Memorial Tribute
- Steve Carell
- Self - Presenter
- Helen Mirren
- Self - Nominee
- Samuel L. Jackson
- Self - Presenter
- Tim Robbins
- Self - Presenter
- Meryl Streep
- Self - Nominee
- Sean Penn
- Self - Presenter
- Steve Martin
- Self - Host
- Ally Sheedy
- Self - John Hughes Tribute
- Colin Firth
- Self - Nominee & Presenter
- Chris Pine
- Self - Presenter
- Anthony Michael Hall
- Self - John Hughes Tribute
- Vera Farmiga
- Self - Nominee & Presenter
- Ryan Bingham
- Self - Winner
- Carey Mulligan
- Self - Nominee & Presenter
- Fisher Stevens
- Self - Winner
- Michael Sheen
- Self - Presenter
- Jeremy Renner
- Self - Nominee
- Christoph Waltz
- Self - Winner
- Mickey Rooney
- Self - Audience Member
- Peter Sarsgaard
- Self - Presenter
- Brittany Murphy
- Self - Memorial Tribute
- Natasha Richardson
- Self - In Memoriam
- Penélope Cruz
- Self - Nominee & Presenter
- Jennifer Lopez
- Self - Presenter
- Edward Asner
- Self - Audience Member / Carl Fredricksen
- Virginia Madsen
- Self
- Patrick Swayze
- Johnny Castle / Sam Wheat - In Memoriam (archive footage)
- Christopher Plummer
- Self - Nominee
- Eli Roth
- Self
- Molly Ringwald
- Self - John Hughes Tribute
- Matthew Broderick
- Self - John Hughes Tribute
- Sam Worthington
- Self - Presenter
- James Cameron
- Self - Nominee
- Alec Baldwin
- Self - Host
- Sarah Jessica Parker
- Self - Presenter
- Pedro Almodóvar
- Self - Presenter
- Maggie Gyllenhaal
- Self - Nominee
- Taylor Lautner
- Self - Presenter
- Mario Lopez
- Self
- Tyler Perry
- Self - Presenter
- Forest Whitaker
- Self - Presenter
- Neil Patrick Harris
- Self - Performer
- Queen Latifah
- Self - Presenter
- Lauren Bacall
- Self - Honorary Oscar Recipient
- Fred Astaire
- Self
- Tina Fey
- Self - Presenter
- Kathryn Bigelow
- Self - Winner
- Ethan Coen
- Self - Nominee
- Judd Nelson
- Self - John Hughes Tribute
- Christopher McDonald
- Self
- Jon Cryer
- Self - John Hughes Tribute
- Miley Cyrus
- Self - Presenter
- Barbra Streisand
- Self - Presenter
- David Carradine
- Self - In Memoriam
- Michael Jackson
- Self / Scarecrow - In Memoriam (archive footage)
- Bruno Campos
- Prince Naveen
- Jason Reitman
- Self - Nominee
- Suzy Amis
- Self - Audience Member
- Harvey Weinstein
- Self
- Mariah Carey
- Self
- Dom DeLuise
- Self / Bernie the Agent - In Memoriam (archive footage)
- Roger Corman
- Self - Honorary Award Recipient
- Jennifer Jones
- Self - In Memoriam
- Gabourey Sidibe
- Self - Nominee
- Lenny Kravitz
- Self
- Tom Ford
- Self - Presenter
- Fred Melamed
- Self
- Ivan Reitman
- Self - Nominee
- Oprah Winfrey
- Self - Presenter
- Michael Giacchino
- Self - Winner
- John Lasseter
- Self
- Ron Silver
- Self - In Memoriam
- Karl Malden
- Self - In Memoriam
- Georgina Chapman
- Self - Audience Member
- Taylor Hackford
- Self
- Mo'Nique
- Self - Winner
- Marc Anthony
- Self
- Lee Daniels
- Self - Nominee
- Susan Downey
- Self - Audience Member
- Pete Docter
- Self - Winner
- Joseph Wiseman
- Self - In Memoriam
- Ben Stein
- Economics Teacher
- Éric Rohmer
- Self - In Memoriam
- Betsy Blair
- Self - In Memoriam
- Michael-Leon Wooley
- Louis
- Alexandre Desplat
- Self
- Bob Peterson
- Dug
- Kathryn Grayson
- Self - In Memoriam
- David Frankel
- Self
- Sandy Powell
- Self - Winner
- Juan José Campanella
- Self - Winner
- Jon Landau
- Self - Nominee
- Mark Boal
- Self - Winner
- James Taylor
- Self - Performer
- Mauro Fiore
- Self - Winner
- Jack Cardiff
- Self - In Memoriam
- Barbara Walters
- Self - Animated Characters Interviewer
- Roy Edward Disney
- Self - In Memoriam
- T Bone Burnett
- Self - Winner
- Lou Jacobi
- Self - In Memoriam
- Joel Harlow
- Self - Winner
- Robert Stromberg
- Self - Winner
- Larry Gelbart
- Self - In Memoriam
- Horton Foote
- Self - In Memoriam
- Rick Carter
- Self - Winner
- Ken Annakin
- Self - In Memoriam
- Howard Zieff
- Self - In Memoriam
- Budd Schulberg
- Self - In Memoriam
- Greg Shapiro
- Self - Winner
- Barney Burman
- Self - Winner
- Joe Letteri
- Self - Winner
- Geoffrey Fletcher
- Self - Winner
- Army Archerd
- Self - In Memoriam
- Louie Psihoyos
- Self - Winner
- Joachim Back
- Self - Winner
- David Brown
- Self - In Memoriam
- Bob Murawski
- Self - Winner
- Paul N.J. Ottosson
- Self - Winner
- Roger Ross Williams
- Self - Winner
- Giovanni Jackson
- Self
- Andrew R. Jones
- Self - Winner
- Haylee Roderick
- Dancer
- Richard Baneham
- Self - Winner
- Tullio Pinelli
- Self - In Memoriam
- Richard O'Barry
- Self
- Joy Michelle Moore
- Self - Audience Member
- Christen Mooney
- Aisling
- Pablo Ferro
- Self - Audience Member
- Stephen Rosenbaum
- Self - Winner
- Gareth Wigan
- Self - in memoriam
- Jaime Monroy
- Red Carpet TV Host
- Chris Innis
- Self - Winner
- Simon Channing Williams
- Self - In Memoriam
- Xoel Pamos
- Self
- Jacquelyn Dowsett
- Dancer
- Anastasia Masaro
- Self - Nominee
- Daniel Melnick
- Self - In Memoriam
- Fabrice Joubert
- Self - Nominee
- Tivi Magnusson
- Self - Winner
- Yvonne Reyes
- Self
- Kim Sinclair
- Self - Winner
- Nicolas Schmerkin
- Self - Winner
- Mindy Hall
- Self - Winner
- Rod L Harrell
- Self
- Gina Tuttle
- Announcer
- Kirk Kelly
- Self
- Ray Beckett
- Self - Winner
- Josh Wood
- Self
- Elinor Burkett
- Self - Co- Winner
- Liinda Garisto
- Opening number dancer
- Antonio Banderas
- Self - Audience Member
- Javier Bardem
- Self - Audience Member
- Dana Barron
- Audrey Griswold
- Mariela Besuievsky
- Self
- Christie Brinkley
- The Girl in the Ferrari
- John Candy
- Buck Russell / Danny Muldoon / Del Griffith (archive footage) (uncredited)
- Chevy Chase
- Clark Griswold
- Brian Corsetti
- Self - Correspondent
- Shane Bitney Crone
- Self
- Jamie Lee Curtis
- Laurie Strode
- Beverly D'Angelo
- Ellen Griswold
- Emilio Estevez
- Andrew Clark
- Anne Fletcher
- Self
- Guillermo Francella
- Self
- Brian Geraghty
- Self - Audience Member
- Jennifer Grey
- Frances 'Baby' Houseman / Jeanie Griswold (archive footage) (uncredited)
- Melanie Griffith
- Self - Audience Member
- Gerardo Herrero
- Self
- Maurice Jarre
- Self - Memorial Tribute
- Stephen Lang
- Self - Audience Member
- Janet Leigh
- Marion Crane
- Anthony Mackie
- Self - Audience Member
- Heather O'Rourke
- Carol Anne Freeling
- Guy Pearce
- Self - Audience Member
- Anthony Perkins
- Norman Bates
- Joe Pesci
- Harry
- CCH Pounder
- Self - Audience Member
- Sapphire
- Self - Audience Member
- Roy Scheider
- Brody
- Jane Seymour
- Self - Audience Member
- Jean Simmons
- Self - In Memoriam
- Daniel Stern
- Marv
- Michael Stuhlbarg
- Self - Audience Member
- Rita Wilson
- Self - Audience Member
