- Charles Boyer
- Paul Orman
- Rita Hayworth
- Ethel Halloway
- Ginger Rogers
- Diane
- Henry Fonda
- George
- Charles Laughton
- Charles Smith
- Edward G. Robinson
- Avery L. 'Larry' Browne
- Paul Robeson
- Luke
- Ethel Waters
- Esther
- Eddie 'Rochester' Anderson
- Reverend Lazarus
- Thomas Mitchell
- John Halloway
- Eugene Pallette
- Luther
- Cesar Romero
- Harry Wilson
- Gail Patrick
- Ellen
- Roland Young
- Edgar
- Marion Martin
- 'Squirrel'
- Elsa Lanchester
- Elsa (Mrs Charles) Smith
- Victor Francen
- Arturo Bellini
- George Sanders
- Williams
- James Gleason
- Joe
- Harry Davenport
- Professor Lyons
- J. Carrol Naish
- Burglar
- Hall Johnson Choir
- Offscreen Singers (Robeson sequence)
- Frank Orth
- Secondhand Clothes Dealer (Rogers sequence)
- Christian Rub
- Cello Player (Laughton sequence)
- Sig Arno
- Piccolo Player (Laughton sequence)
- James Rennie
- H.R. 'Hank' Bronson (Robinson sequence)
- Harry Hayden
- 'Soupy' Davis (Robinson sequence)
- Morris Ankrum
- Judge Tom Barnes (Robinson sequence)
- Donald Douglas
- 'Hen 'Henderson (Robinson sequence)
- Mae Marsh
- Molly (Robinson sequence)
- Clarence Muse
- Grandpa (Robeson sequence)
- George Reed
- Christopher (Robeson sequence)
- Cordell Hickman
- Little Nicodemus (Robeson sequence)
- Paul Renay
- 'Spud' Johnson (Robinson sequence)
- Barbara Lynn
- Mary (Robinson sequence)
- Adeline De Walt Reynolds
- Elsa's Old Mother (Laughton sequence)
- Helene Reynolds
- Actress (Boyer sequence)
- John Alban
- Concertgoer
- Rene Austin
- Susan (Laughton sequence)
- Olive Ball
- Shantytown Woman (Robeson sequence)
- Monica Bannister
- Concertgoer (Laughton sequence)
- Bonnie Bannon
- Concertgoer (Laughton sequence)
- Don Beddoe
- Whistler
- Jerry Bergen
- Little Man (Fields sequence)
- Joseph E. Bernard
- Wally, the Postman (Robinson sequence)
- Edward Biby
- Party Guest
- Ted Billings
- Man at City Mission (Robinson sequence)
- William A. Boardway
- Concertgoer
- Buster Brodie
- Call Boy (Laughton sequence)
- Don Brodie
- Whistler at Mission (Robinson sequence)
- Jack Chefe
- Mr. Martelli (Boyer sequence)
- Rita Christiani
- Young woman in Embrace (Robeson sequence)
- Chester Clute
- Mr. Langehanke (Fields sequence)
- Gino Corrado
- Spectator at Concert (Laughton sequence)
- Oliver Cross
- Concertgoer
- Frank Dae
- Elderly Man (Laughton sequence)
- Marcel Dalio
- 2nd Salesman at Santelli's (Fields sequence)
- Frank Darien
- Elsa's Old Father (Laughton sequence)
- Sayre Dearing
- Man at Reunion (Robinson sequence)
- Hazel Dohlman
- Concertgoer
- Maggie Dorsey
- Woman (Robeson sequence)
- Margaret Dumont
- Mme. Langehanke (Fields sequence)
- Dot Farley
- Party Guest (Fields sequence)
- W.C. Fields
- Professor Pufflewhistle (Fields sequence)
- Bess Flowers
- Concertgoer (Laughton sequence)
- Alberta Gary
- Shantytown Woman (Robeson sequence)
- Slim Gaut
- Man at City Mission
- Herschel Graham
- Concertgoer
- Charles H. Gray
- Rod (Robeson sequence)
- Robert Greig
- Lazar the Tailor (Boyer sequence)
- Jester Hairston
- Shantytown Man (Robeson sequence)
- Stuart Hall
- Reunion Guest
- William Halligan
- Oliver Webb (Boyer sequence)
- Rondo Hatton
- Party Guest (Fields sequence)
- Joe Hinds
- Man at City Mission
- Esther Howard
- Woman Bumming Cigarette from Joe (Robinson sequence)
- Philip Hurlic
- Jeff (Robeson sequence)
- William Irving
- Victim of Drink (Fields sequence)
- Frank Jaquet
- Oboist (Laughton sequence)
- Jack W. Johnston
- Concertgoer
- John Kelly
- Burglar (Robeson sequence) / Driver (Robeson sequence) (uncredited)
- Kenner G. Kemp
- Gambling House Patron
- Colin Kenny
- Concertgoer (Laughton sequence)
- Mike Lally
- Bus Passenger
- Ella Mae Lashley
- Woman (Robeson sequence)
- Johnny Lee
- Shantytown Carpenter (Robeson sequence)
- Connie Leon
- Mary (Rogers sequence)
- Max Linder
- Concertgoer
- Pat McKee
- Bartender
- Charles Meakin
- Concertgoer
- Harold Miller
- Man at Reunion (Robinson sequence)
- Bert Moorhouse
- Concertgoer (Laughton sequence)
- Forbes Murray
- Dignified Man (Laughton sequence)
- Lonnie Nichols
- Brad (Robeson sequence)
- Edgar Norton
- Jessup - Langehanke's Butler (Fields sequence)
- Tom O'Grady
- Concert Latecomer (Laughton sequence)
- Manuel ParÃs
- Doorman at Gambling Casino
- Alexander Pollard
- Waiter
- Paul Power
- Concertgoer
- Catherine Price
- Concertgoer
- Fred Rapport
- Concertgoer
- Suzanne Ridgway
- Concertgoer (Laughton sequence)
- Cyril Ring
- Assistant Tailor (Boyer sequence)
- Dewey Robinson
- Charles Smith's Bullying Boss (Laughton sequence)
- Loretta Russell
- Party Guest
- Archie Savage
- Shantytown Man (Robeson sequence)
- Phil Silvers
- 1st Salesman at Santelli's (Fields sequence)
- Ted Stanhope
- Henderson's Chauffeur (Robinson sequence)
- Count Stefenelli
- Concertgoer (Laughton sequence)
- Bert Stevens
- Assistant Tailor (Boyer sequence)
- Charles Tannen
- Pilot (Robeson sequence)
- Curly Twiford
- Bird Man (Laughton sequence)
- Ellinor Vanderveer
- Party Guest (Fields sequence)
- Laura Vaughn
- Woman (Robeson sequence)
- Dorothy Vernon
- Party Guest (Fields sequence)
- Blue Washington
- Shantytown Man (Robeson sequence)
- Charles Williams
- Orman's Bespectacled Agent (Boyer sequence)
- Eric Wilton
- Halloway's Butler (Boyer sequence)
- Will Wright
- Old Concertgoer (Laughton sequence)
