- Clark Williams
- Tailspin Tommy Tompkins
- Jean Rogers
- Betty Lou Barnes
- Delphine Drew
- Inez Casmetto
- Noah Beery Jr.
- 'Skeeter' Milligan
- Bryant Washburn
- Ned Curtis
- Pat J. O'Brien
- Milt Howe
- Herbert Heywood
- Manuel Casmetto
- Matthew Betz
- Horace Raymore
- Paul Ellis
- Enrico Garcia [Chs. 2-9]
- Harry Worth
- Don Alvarado Casmetto
- Manuel López
- Gomez [Chs. 3-6, 8-12]
- Charles A. Browne
- Paul Smith [Chs. 1-2]
- James P. Burtis
- Bill McGuire
- Helen Brown
- Mrs. Tompkins [Ch. 1]
- Frank Mayo
- Dirigible Captain [Ch. 1]
- Fritzi Brunette
- Dinner Guest [Ch. 1]
- Frank Clarke
- Flyer
- Ethan Laidlaw
- Henchman
- Ted Billings
- Airport Attendant
- John Bose
- Workman
- Don Brodie
- Three Point Radio Operator [Chs. 1-2]
- Morgan Brown
- Controller
- Horace B. Carpenter
- Townsman [Ch. 1]
- George DeNormand
- Crewman Smith [Chs. 11-12]
- William Desmond
- Foreman Burke [Chs. 7-9,11-12]
- Charles Dorety
- Dirigible Radio Operator [Ch. 1]
- Lew Kelly
- Victor Martin
- Charles King
- Burly Henchman in Pith Helmet [Chs. 3, 5, 6]
- John Marlin
- Workman
- Manuel ParÃs
- Frondo - Gang Aviator [Ch. 2]
- Buddy Roosevelt
- Nefarious Mechanic [Ch. 4]
- Slim Whitaker
- Captain Larsen [Chs. 11,12]
