- Amy Sedaris
- Jerri Blank
- Paul Sedaris
- Bus Driver
- Chandra Wilson
- Inmate
- Kristy Thomas
- Inmate
- Dee Finley
- Inmate
- Deborah Rush
- Sara Blank
- Ian Holm
- Dr. Putney
- Dan Hedaya
- Guy Blank
- Joseph Cross
- Derrick Blank
- Elisabeth Harnois
- Monica
- Alexis Dziena
- Melissa
- Ivette Dumeng
- Melanie
- Carlo Alban
- Megawatti
- Greg Hollimon
- Principal Blackman
- Hechter Ubarry
- Nico
- Allison Janney
- Alice
- Philip Seymour Hoffman
- Henry
- Stephen Colbert
- Chuck Noblet
- Paul Dinello
- Geoffrey Jellineck
- Dolores Duffy
- Iris Puffybush
- Maria Thayer
- Tamela 'Tammi' Littlenut
- Timothy Hsu
- Mascott
- Tom Guiry
- P John
- Wallace Little
- Trace
- David Pasquesi
- Stew
- Sarah Jessica Parker
- Peggy Callas
- Matthew Broderick
- Roger Beekman
- David Rakoff
- Boswell
- Cal Robertson
- Les Tuckles
- Billy Erb
- Teacher
- Callie Thorne
- Teacher
- Chris Pratt
- Brason
- Sarah Thyre
- Coach Wolf
- Kristen Johnston
- Coach Divers
- Justin Theroux
- Carlo Honklin
- Lian Moy
- Lian
- Olivia Oguma
- Olivia
- Jeremy Chu
- Jeremy
- Evelyn McGee
- Clair Noblet
- Alicia Ashley
- Rolanda
- Randy Blair
- Student
- Jonah Bobo
- Shamus Noblet
- Leanne Cabrera
- Gym Student
- Lionel Anthony Cook
- High School Student
- Angelina Cruz
- Carmen
- Thomas Daniel
- Parent
- Lorena David
- Teacher
- Ryan Donowho
- Stanley
- Logann Grayce
- (uncredited)
- Rob Hinderliter
- Squat Thrust Team Captain
- Tony Lagarto
- Buster Highman
- Christopher Larkin
- Kim
- Tony Longoria
- Flatpoint Faculty
- Meghan Maro
- High School Student
- Todd Oldham
- Mr. Oldham
- Sarah Peters
- Student
- Michael Rivera
- Manaco
- Timothy Roscoe
- Preppy Student
- Jessica Rothert
- High School Student
- Gina Vetro
- Prison Inmate
- Mike Yedwab
- Varsity Squat Thrust Member
