- Steven R. McQueen
- The Kid (segment "Club Soda")
- Joe Mantegna
- Mike (segment "Club Soda")
- Michael Rispoli
- Jack (segment "Club Soda")
- Louis Gossett Jr.
- Doc (segment "Club Soda")
- Laurie Fortier
- Bunny (segment "Club Soda")
- James Gandolfini
- The Man (segment "Club Soda")
- Billy St. John
- Neil (segment "Club Soda")
- John Barillaro
- The Repairman (segment "Club Soda")
- Marivel Decker
- Carla (segment "Club Soda")
- Ken Hudson Campbell
- Chester (segment "Street of Pain")
- Eric Stonestreet
- Floyd (segment "Street of Pain")
- Kathleen Campbell
- Cheryl (segment "Street of Pain")
- Steve Carell
- Mark (segment "Street of Pain")
- Ian Gomez
- Beau (segment "Street of Pain")
- Emmy Laybourne
- Merideth (segment "Street of Pain")
- Dyllan Christopher
- Young Mark (segment "Street of Pain")
- Nathan Norton
- Young Beau (segment "Street of Pain")
- Erik Torppe
- Young Chester (segment "Street of Pain")
- Liam Welch
- Young Floyd (segment "Street of Pain")
- Josh Hartnett
- Gianni (segment "Member")
- Scott Caan
- Hayden Field (segment "Life Makes Sense If You're Famous")
- Erik MacArthur
- Owen Peedmen (segment "Life Makes Sense If You're Famous")
- Paul Walker
- Mikey (segment "Life Makes Sense If You're Famous")
- Will McCormack
- Dean (segment "Life Makes Sense If You're Famous")
- Maya James
- Lisa Mancini (segment "Life Makes Sense If You're Famous")
- Desmond Harrington
- Jay (segment "Life Makes Sense If You're Famous")
- Robert Bagnell
- (segment "Life Makes Sense If You're Famous")
- Fanshen Cox
- Maximina (segment "L.A. Knights")
- Paris Hilton
- Sadie (segment "L.A. Knights")
- Sole Alberti
- Lou (segment "L.A. Knights")
- Jesse Woodrow
- Iowa Guy (segment "L.A. Knights")
- Jason Shaw
- Fantasy Guy (segment "L.A. Knights")
- Matt Walthard
- Bartender (segment "L.A. Knights")
- Jarred Marsh
- Cheezy Guy #1 (segment "L.A. Knights")
- Matthew Roseman
- Cheezy Guy #2 (segment "L.A. Knights")
- Jonathan Dane
- Cheezy Guy #3 (segment "L.A. Knights")
- Meredith Chin
- DJ (segment "L.A. Knights")
- Betsy Miller
- Promoter Lady (segment "L.A. Knights")
- Brad Grubaugh
- Bouncer (segment "L.A. Knights")
- Remy G.
- Hot Car Guy (segment "L.A. Knights")
- Alisen Richmond-Peck
- Claire (segment "The Little Things")
- Ioan Gruffudd
- Simon (segment "The Little Things")
- Aaron Douglas
- The Boss (segment "The Little Things")
- Alistair Abell
- Bob (segment "The Little Things")
- Wedil David
- Barfly (segment "Club Soda")
- Jack Kissell
- (archive footage) (as Jack Kissel)
