- Steven Strait
- Sheerluck Holmes / LiamBoy (Liam the Human)
- Phil Vischer
- Dr. Watson / Sheriff (Bob the Tomato) / Don Quixote / Prime Minister (Archibald Asparagus) / Ponacho / John Spud (Mr. Lunt) / Bill Trout / Manager (Mr. Neezer) / King (Pa Grape) / Jimmy Gourd / French Peas / Announcer (voice)
- Mike Nawrocki
- Jerry Gourd / French Peas / Cheese E. Rodent (voice)
- Jim Poole
- Scotland Yard Policeman (Scooter)
- Anthony Field
- Ben Cookie
- Murray Cook
- Chris Saners
- Cody Linley
- Young Tyler
- Greg Smith
- Young Sheerluck
- Ken Fresley
- Investigator
- Meg Munro
- Maid
- Paul Field
- Cop
- Jacqui Bead
- Lady Past Sheerluck
- Michel Hughes
- Meteorologist Jamey
- Andrew McIlroy
- Investor at Backroom
- Thom Strait
- Gated Community Singer
- Justin Allen
- Gated Community Singer
- Calum Gittins
- Sheerluck Holmes Lookalike
- Penn Badgley
- Sheerluck Holmes Lookalike
- Ray Strait
- Customer
- Chase Strait
- Customer
- Megan Strait
- Customer
- Georgia Munro Cook
- Customer
- Hamish Munro Cook
- Customer
- Dominic Field
- Comedy Kid
- Joseph Field
- Comedy Kid
