- Marc Sandler
- Simon Penn
- Sarah Rachel Isenberg
- CJ Keyes
- Michael Denney
- Eddie 'Killer' Kuzinski
- Jason Moscartolo
- Matty Shea
- Linda Amendola
- Jenny Penn
- Vinny De Vingo
- Lou, Kuzinski's Manager
- Alex Martinez Wallace
- Benny
- Ed Peed
- Detective Fraeter
- Hira Ambrosino
- Dr. Susan Willem
- Dan Marois
- Dr. Dan
- Josh Norton
- Tall Boy
- Edwin W. Thurston
- Joe
- Norman Bunin
- Mir
- Steve Bortagis
- Fat Greg
- Bert Brown
- Ring Announcer (CJ / Kuzinski)
- Eric Allen
- Heavyweight Opponent / Ghostly Spectre
- Thomas Commeret
- Ring Announcer (CJ / Chamal)
- Adrianna Galic
- Bar Singer
- Daniel Kaplan
- Intern
- Mary McIlvaine
- Night Nurse
- Gary Boynton
- Harry
- Darrin Reid
- Security Guard
- Greg Alldredge
- Fat Patrolman
- Tony Anaman
- Ring Doctor
- John Jenkins
- Ref (CJ / Kuzinski)
- Giovanni Cappello
- Officer Reid
- James Tanabe
- Rodge
- Joni Yaras
- Chamal
- Martin Petrovich
- Kuzinski's Ref
- Lorne Therrian
- Kuzinski's Challenger
- Melissa Greer
- Waitress
- Jill Harrigan
- Opponent #1
- Dan Abbott
- Ref (CJ / Opponent #1)
- Joseph Bukowski
- Chamal's Trainer
- David Collupy
- Man with Camera
- Bill Steven McLean
- Ref
- Seth Wolfe
- Rowdy Guy
- Bill Jordan
- Montage Ref
- Judy Castonguay
- CJ's Opponent
- Joanne White
- CJ's Opponent
- Linda Baptista
- CJ's Opponent
- Saddie Holm
- CJ's Opponent
- Paul Grandmaison
- Grungy Doctor
- Terri Caito
- Rowdy Woman
- Ross Malfa
- Orderly
- Rosaire LaFontaine
- Elderly Patient
- Bruce Gerry
- Plainclothes Officer
- Carol Sanborn
- Add'l Nurse
- Tina Konstantoulakis
- Spectator
- Darrin Reed
- Security guard
- William T.M. Taylor
- Chreering Crowd member / extra
- Michelle Saint Moore
- Kuzinski's Entourage
- Jennifer Soldner
- Crowd Member
