- David Spade
- Self / Various (archive footage)
- Fred Armisen
- Spook Peterson
- Tom Arnold
- Dad
- Roseanne Barr
- Self
- Dana Carvey
- Bob Dylan
- Ellen Cleghorne
- Airline Passenger
- Tom Davis
- Airline Passenger
- Rachel Dratch
- Various
- Chris Farley
- Self / Various Characters (archive footage) (uncredited)
- Will Ferrell
- Self
- Tina Fey
- Yvonne Shirley
- Will Forte
- Tan or Grime Guy
- Sara Gilbert
- Missy
- Jeff Goldblum
- Self
- Darrell Hammond
- Skeeter
- Phil Hartman
- Various
- Teri Hatcher
- David Spade
- Helen Hunt
- Total Bastard Airlines Stewardess
- Melanie Hutsell
- Airline Passenger
- Norm MacDonald
- Airline Passenger
- Steve Martin
- Self
- Tim Meadows
- Airline Passenger
- Seth Meyers
- Various
- Dennis Miller
- Self
- Jay Mohr
- Airline Passenger
- Mike Myers
- Various
- Kevin Nealon
- Michael Tassoni
- Jason Patric
- Kevin
- Sean Penn
- Self
- Matt Piedmont
- Audience Member
- Amy Poehler
- Various
- Rob Riggle
- Various
- Maya Rudolph
- Employee
- Adam Sandler
- Various
- Horatio Sanz
- Vin Diesel
- Rob Schneider
- Various
- Sarah Silverman
- Airline Passenger
- Julia Sweeney
- Elderly Woman
- Steven Tyler
- Self
- Christopher Walken
- Self
