- Clark Gable
- Duke Bradley
- Jean Harlow
- Carol Clayton
- Lionel Barrymore
- Grandpa Clayton
- Frank Morgan
- Jesse Kiffmeyer
- Walter Pidgeon
- Hartley Madison
- Una Merkel
- Fritzi
- Cliff Edwards
- Tip
- George Zucco
- Dr. Harmsworth Bierd
- Jonathan Hale
- Frank Clayton
- Hattie McDaniel
- Rosetta
- Frankie Darro
- Dixie Gordon
- Henry Stone
- Hand-Riding Hurley
- Pat West
- Horse Owner
- Jann Andrews
- One of the Hurley Twins
- Kathleen Andrews
- One of the Hurley Twins
- Sheila Andrews
- One of the Hurley Twins
- Franklyn Ardell
- Passenger on Train
- Herbert Ashley
- Bartender
- Hooper Atchley
- Voice of Bidder
- George Atkinson
- Train Passenger
- Joseph E. Bernard
- Auction Attendant
- Edward Biby
- Train Passenger
- Johnny Bland
- Black Man
- William Carey
- Passenger on Train
- George Chandler
- Cameraman
- George Cochran
- Black Man
- Diane Cook
- Passenger on Train
- Oliver Cross
- Party Guest
- Edgar Dearing
- Medbury the Trainer
- Mary Dees
- Carol Clayton (after Jean Harlow's Death)
- Drew Demorest
- Cameraman
- Dudley Dickerson
- Mr. Miles
- Sam Flint
- Racetrack Judge
- Four Esquires
- The Four Esquires in Saratoga Number
- Charley Foy
- Valet
- Irene Franklin
- Passenger on Train
- Ruth Gillette
- Mrs. Pearl Hurley
- Jesse Graves
- Train Porter
- Harrison Greene
- Clipper
- Stuart Hall
- Party Guest
- Margaret Hamilton
- Maizie
- Sam Harris
- Railbird
- John Hyams
- Horse Owner
- Si Jenks
- Gardener
- Jack W. Johnston
- Nightclub Patron
- Robert Emmett Keane
- R.J. Wittrock
- Kenner G. Kemp
- Nightclub Extra
- Carl M. Leviness
- Party Guest
- Billy McClain
- Butler
- Frank McGlynn Sr.
- Ed Kenyon
- Frank McLure
- Train Passenger
- Charles R. Moore
- Bartender on Train
- Bert Moorhouse
- Horse Race Bit
- Forbes Murray
- Pullman Steward
- Patsy O'Connor
- Katie Hurley
- Dennis O'Keefe
- Second Bidder / Dancer at Party (uncredited)
- Lionel Pape
- Horse Owner at Party
- Wanda Perry
- Girl at the Racetrack
- Paul Power
- Party Guest
- Catherine Price
- Racetrack Spectator
- George Reed
- Butler
- Gus Reed
- Preston
- Bert Roach
- Passenger on Train
- Walt Robbins
- Limpy
- Mel Ruick
- Tout
- Grace Saxon
- Singer
- Scott Seaton
- Nightclub Patron
- Gertrude Simpson
- Undetermined Secondary role
- Carl Stockdale
- Boswell
