- Masaharu Fukuyama
- Â Ryoma Sakamoto 48 episodes, 2010
- Masaomi Kondô
- Â Yamauchi Yodo 48 episodes, 2010
- Teruyuki Kagawa
- Â Yataro Iwasaki 45 episodes, 2010
- Munetaka Aoki
- Â Gotou Shoujirou 40 episodes, 2010
- Jun Kaname
- Â Sonojo Sawamura 31 episodes, 2010
- Takeru Satoh
- Â Izo Okada 28 episodes, 2010
- Atsushi Korechika
- Â Toranosuke Chiya 27 episodes, 2010
- Shinobu Terajima
- Â Otome Sakamoto 26 episodes, 2010
- Daijirô Kawaoka
- Â Taro Takamatsu 26 episodes, 2010
- Shôsuke Tanihara
- Â Kogoro Katsura 25 episodes, 2010
- Keizô Kanie
- Â Yajiro Iwasaki 25 episodes, 2010
- Mitsuko Baishô
- Â Miwa Iwasaki 24 episodes, 2010
- Yô Ôizumi
- Â Chojiro Kondo 23 episodes, 2010
- Yûta Hiraoka
- Â Yonosuke Mutsu 22 episodes, 2010
- Takuma Otoo
- Â Kameyata Mochizuki 22 episodes, 2010
- Wakako Shimazaki
- Â Chino Sakamoto 21 episodes, 2010
- Tetta Sugimoto
- Â Gonpei Sakamoto 20 episodes, 2010
- Hiroyuki Miyasako
- Â Shujiro Hirai 20 episodes, 2010
- Daisuke Honda
- Â Seihei Mochizuki 20 episodes, 2010
- Shigeru Saiki
- Â Katsukiyo Itakura 20 episodes, 2010
- Chieko Matsubara
- Â Iyo Sakamoto 19 episodes, 2010
- Tetsushi Tanaka
- Â Yoshinobu Tokugawa 19 episodes, 2010
- Kaoru Okunuki
- Â Tomi Takechi 18 episodes, 2010
- Katsumi Takahashi
- Â Kichinosuke Saigo 17 episodes, 2010
- Maiko
- Â Kise Iwasaki 17 episodes, 2010
- Shota Taniguchi
- Â Sakutaro Nakajima 17 episodes, 2010
- Ryôta Matsumura
- Â Umanosuke Shingu 17 episodes, 2010
- Ryôko Hirosue
- Â Kao Hirai 14 episodes, 2010
- Pierre Taki
- Â Hironojo Mizobuchi 14 episodes, 2010
- Yôko Maki
- Â Oryo 13 episodes, 2010
- Atsuko Maeda
- Â Harui Sakamoto 13 episodes, 2010
- Ken'ichi Takitô
- Â Komatsu Kiyokado 13 episodes, 2010
- Kimiko Yo
- Â Kei Oura 12 episodes, 2010
- Tetsuya Takeda
- Â Katsu Kaishu 12 episodes, 2010
- Joe Hyûga
- Â Katsutaro Tayama 12 episodes, 2010
- Yû Aoi
- Â Omoto 11 episodes, 2010
- Hirotarô Honda
- Â Kendo Kozone 11 episodes, 2010
- Ryo Ishibashi
- Â Masahiro Asahina 10 episodes, 2010
- Yûsuke Iseya
- Â Shinsaku Takasagi 10 episodes, 2010
- Tamiyo Kusakari
- Â Ko Sakamoto 10 episodes, 2010
- Kazuyuki Matsuzawa
- Â Matabei Morishita 10 episodes, 2010
- Satoshi Matsuda
- Â Toshizo Hijikata 9 episodes, 2010
- Tarô Suruga
- Â Taro Nogami 9 episodes, 2010
- Rakuto Tochihara
- Â Soji Okita 9 episodes, 2010
- Yuma Sasano
- Â Yanosuke Iwasaki (young) 9 episodes, 2010
- Min Tanaka
- Â Toyo Yoshida 8 episodes, 2010
- Shihori Kanjiya
- Â Sana Chiba 8 episodes, 2010
- Ikkei Watanabe
- Â Jutaro Chiba 8 episodes, 2010
- Yoshiki Arizono
- Â Yonosuke Sato / ... 8 episodes, 2010
- Toranosuke Katô
- Â Mita Inoue 8 episodes, 2010
- Hiroyuki Onoue
- Â Shunsuke Ito 8 episodes, 2010
- Satoru Kawaguchi
- Â Heikurou Kawaguchi 8 episodes, 2010
- Kenta Kiritani
- Â Kurata Ike 7 episodes, 2010
- Kyôsuke Yabe
- Â Genzui Kusaka 7 episodes, 2010
- Kôtarô Satomi
- Â Sadakichi Chiba 7 episodes, 2010
- Toshio Kakei
- Â Shinzo Miyoshi 7 episodes, 2010
- Isao Natsuyagi
- Â Matsudaira Yoshinaga 6 episodes, 2010
- Takaya Kamikawa
- Â Shintaro Nakaoka 6 episodes, 2010
- Jeffrey Rowe
- Â William J. Alt 6 episodes, 2010
- Yôsuke Saitô
- Â Tadamasa Oguri 6 episodes, 2010
- Mantarô Koichi
- Â Wasuke 6 episodes, 2010
- Tomoharu Hasegawa
- Â Katamori Matsudaira 6 episodes, 2010
- Taizô Harada
- Â Isami Kondo 6 episodes, 2010
- Kiyoshi Kodama
- Â Hachihei Sakamoto 6 episodes, 2010
- Kin Sugai
- Â Tomo Takechi 5 episodes, 2010
- Manabu Hamada
- Â Akira Sakazaki 5 episodes, 2010
- Andrez Bergen
- Â Dutch Trader 5 episodes, 2010
- Mitsuhiro Oikawa
- Â Toshimichi Okubo 4 episodes, 2010
- Tetsuya Ushio
- Â Noriyasu Matsudaira 4 episodes, 2010
- Tortoise Matsumoto
- Â John Manjiro 4 episodes, 2010
- Takeshi Masu
- Â Masahiro Abe 4 episodes, 2010
- Yoshikazu Kawabuchi
- Â Hiro Chikakuze 4 episodes, 2010
- Gary J. Wolff
- Â Thomas Blake Glover's butler 4 episodes, 2010
- Kazumasa Taguchi
- Â Tadamasa Makino 4 episodes, 2010
- Tim Wellard
- Â Thomas Blake Glover 4 episodes, 2010
- Tarô Suwa
- Â Takezo 3 episodes, 2010
- Shin'ya Ôwada
- Â Sorin Miyama 3 episodes, 2010
- Thomas J. Melesky
- Â Perry's Crew Member 3 episodes, 2010
- Dennis D. Zomerhuis
- Â Anton L. C. Portman 2 episodes, 2010
- Shôta Sometani
- Â Toyonori Yamauchi 2 episodes, 2010
- Shirô Namiki
- Â Otsuya 2 episodes, 2010
- Mika Kikuchi
- Â Saki Iwahashi 2 episodes, 2010
- Ayano Moriguchi
- Â Shino 2 episodes, 2010
- Masanobu Sakata
- Â Hiromichi Ido 2 episodes, 2010
- Hiroyuki Konishi
- Â Teizo Miyabe 2 episodes, 2010
- Masashi Arifuku
- Â Hisamitsu Shimazu 2 episodes, 2010
- Jeff Wastila
- Â Harry Smith Parkes 2 episodes, 2010
- Tao Tsuchiya
- Â Otome sakamoto 1 episode, 2010
- Renji Ishibashi
- Â Genba Nagai 1 episode, 2010
- Katsuhisa Namase
- Â Shoin Yoshida 1 episode, 2010
- Takashi Kitadai
- Â Reijiro Ido 1 episode, 2010
- Gregory Pekar
- Â Consular 1 episode, 2010
- Bengal
- Â Neiho Okamoto 1 episode, 2010
- Jirô Dan
- Â Tsunamichi Kashiwabara 1 episode, 2010
- Tatsuomi Hamada
- Â Ryoma Sakamoto 1 episode, 2010
- Mitsuomi Takahashi
- Â Shigekichi Yamawaki 1 episode, 2010
- Nao Oikawa
- Â Prostitute 1 episode, 2010
- Mari Hoshino
- Â Sumi 1 episode, 2010
- Moro Morooka
- Â Otsuki Chikara 1 episode, 2010
- Gô Rijû
- Â Izumi Maki 1 episode, 2010
- Ennosuke Ichikawa IV
- Â Nobuo imai, assassin 1 episode, 2010
- Shôzô Uesugi
- Â Chubee Yamamoto 1 episode, 2010
- Tatsuya Nakamura
- Â Tadasaburo sasaki, assassin 1 episode, 2010
- Tomohiro Waki
- Â Takasaki 1 episode, 2010
- Christopher Pellegrini
- Â Interpreter 1 episode, 2010
- Ryôta Sakanishi
- Â Seisaburo Toyama 1 episode, 2010
- Hideyuki Kasahara
- Â Toranoshin Ikeda 1 episode, 2010
- Bibiru Ohki
- Â Passerby 1 episode, 2010
- Erika Kuroishi
- Â Shizu 1 episode, 2010
- Terry Ito
- Â Hikoma Ueno 1 episode, 2010
- Yôichi Nukumizu
- Â Kian Okagami 1 episode, 2010
- Toshihide Tonesaku
- Â Shinsuke Yoshihiro 1 episode, 2010
- Kensuke Owada
- Â Minekichi 1 episode, 2010
- Shinji Ozeki
- Â Shigenosuke Kaneko 1 episode, 2010
- Gakudai Yamazaki
- Â Sanen Kabayama 1 episode, 2010
- Sion
- Â Assassin 1 episode, 2010
- Cynthia Cheston
- Â Woman at party (uncredited) unknown episodes
