- Elizabeth Daily
- Â Tommy Pickles 7 episodes, 2021
- Cheryl Chase
- Â Angelica Pickles 6 episodes, 2021
- Cree Summer
- Â Susie Carmichael 5 episodes, 2021
- Nancy Cartwright
- Â Chuckie Finster 5 episodes, 2021
- Kath Soucie
- Â Lil DeVille / ... 5 episodes, 2021
- Ashley Rae Spillers
- Â Didi Pickles 4 episodes, 2021
- Natalie Morales
- Â Betty DeVille 1 episode, 2021
- Tony Hale
- Â Chas Finster 1 episode, 2021
- Michael McKean
- Â Grandpa Lou Pickles 1 episode, 2021
- Timothy Simons
- Â Drew Pickles 1 episode, 2021
- Tommy Dewey
- Â Stu Pickles 1 episode, 2021
