- Jericho Rosales
- Manny Pacquaio
- Bea Alonzo
- Jinky / Janet
- Jay Manalo
- Emong
- Bayani Agbayani
- Buboy
- Tirso Cruz III
- Manny's Parent
- Jaclyn Jose
- Manny's Parent
- Jiro Manio
- Young Manny
- Zoren Legaspi
- Business Associate
- Ricky Davao
- Polding Correa
- Polo Ravales
- Bobby
- Gloria Sevilla
- Nanay Parcon
- Dimples Romana
- Emong's Wife
- Jim Pebanco
- Bayani Ocampo
- Tony Mabesa
- Ruben Novales
- Mon Confiado
- Rico Antonio
- Biboy Ramirez
- Eugene Barotag
- Gabb Drilon
- Rogelio
- Richard Quan
- Manny's Uncle
- Czarina Dela Peña
- Isidra
- Pinky Amador
- Jinkee / Janet's Parent
- Emil Sandoval
- Jinkee / Janet's Parent
- Freddie Roach
- American Trainer
- Glaiza De Castro
- Cecille
- Empress Schuck
- Young Isidra
- Bryan Homecillo
- Young Eugene
- Sean Ignacio
- Young Bobby
- Owen Bowen
- Young Rogelio
- Richard Cunanan
- Freddie Roach
- Jon Henderson
- American Manager
- Tony Wells
- American Promoter
- Popoy Bardos
- Emmanuel
- Ethan Flaminiano
- Stephen
- Jethro Ramirez
- Jinkee / Janet's Uncle
- Alvin Anson
- Isidra's Husband
- Andrea Del Rosario
- Manny's Woman 1
- Marla Boyd
- Manny's Woman 2
- Desiree Del Valle
- Manny's Woman 3
- Menggie Cobarrubias
- Manny's Filipino Lawyer
- Michael Garland
- Manny's American Lawyer
- Mike Cassey
- American Promoter's Lawyer
- Chaz Moore
- American Promoter's Lawyer
- Tom Silver
- American Promoter's Lawyer
- Jon Romano
- Manny's Friend
- John Apacible
- Heckler
- Alchris Galura
- Bully - General Santos
- Marco Aytona
- Bully - Manila
- Jet Paz
- Other Young Boxer
- Job Zamora
- Other Young Boxer
- Valerie Concepcion
- Nurse
- Glenn Nepomuceno
- Bouncer
- Genaro Mendoza
- Judge / Bodyguard (as Genaro 'Aro' M. Mendoza)
- John Paul Cadaing
- Manny & Jinkee's Godparent / Wedding Sponser (as Jaypee Cadaing)
- Alice Yumol
- Manny & Jinkee's Godparent / Wedding Sponsor (as Alice Yumul)
- Rycharde Everley
- American Doctor
- Ali Khatibi
- Morales
- Rico Barrera
- Barrera
- Juddha Paolo
- Singsurat
- Dax Alejandro
- Torrecampo
- Gelo Reyes
- Torrejos
- Rey Labo
- Manny's Boxing Opponent
- Baby Lorona Jr.
- Manny's Boxing Opponent
- R.J. Obliosca
- Manny's Boxing Opponent
- Raymond Sermona
- Manny's Boxing Opponent
- Aldrin de Vera
- Young Manny's Boxing Opponent
- R.J. Iringan
- Young Manny's Boxing Opponent
- Anthony Peñalosa
- Emong's Boxing Opponent
- Luisito 'Lui' Sanggalang
- Eugene's Boxing Opponent
- Willy Potter
- American Referee
- Robert Hutton
- American ring Announcer
- Travis Kraft
- American Commentator
- Robert Newell
- American Commentator
- Don Agudo
- Filipino Referee
- Mark Bacho
- Filipino Referee
- Alex De Guzman
- Filipino Referee
- Archel Villamor
- Filipino Referee
- Red Valdez
- Filipino Ring Announcer
- Del Bacho
- Filipino Commentator
- Glenn Evangelista
- Filipino Commentator
- Rey Danseco
- Filipino Commentator
- Rivo Raymundo Nisce
- Doctor
- Pedro Acharon Jr.
- Bodyguard
- Willie L. Malpas
- Boxing Judge 1
- Arcie L. Peña
- Boxing Judge 2
- Raul M. Lumanlan
- Boxing Judge 3
