- Felecia Angelle
- Perona
- Erik Archilla
- Additional Voices
- Greg Ayres
- Cabaji
- Laura Bailey
- Conis
- William Bondurant
- Additional Voices
- Anthony Bowling
- Additional Voices
- Duncan Brannan
- Mr. 3
- Brandon Bristow
- Additional Voices
- Ben Bryant
- Additional Voices
- Patric Carroll
- Additional Voices
- Bob Carter
- Gedatsu
- Martin Cervantes
- Additional Voices
- Andrew Chandler
- Absalom
- Clifford Chapin
- Additional Voices
- Ben Charlson
- Additional Voices
- Eric Cherry
- Additional Voices
- Shigeru Chiba
- Buggy
- Luci Christian
- Nami
- Colleen Clinkenbeard
- Monkey D Luffy
- Kevin Connolly
- Pell
- Adrian Cook
- Additional Voices
- Justin Cook
- Additional Voices
- Chad Cox
- Additional Voices
- Cynthia Cranz
- Onion / Ririka (voice)
- Jin Domon
- Merry
- J.B. Edwards
- Additional Voices
- Moriya Endo
- Cabaji
- Juli Erickson
- Amazon
- Marti Etheridge
- Additional Voices
- Michael Federico
- Additional Voices
- Bill Flynn
- Genzo
- Joey Folsom
- Additional Voices
- Jim Foronda
- Tararan
- Jonathan R. Freeman
- Foxy
- Scott Freeman
- Additional Voices
- Richard George
- Additional Voices
- Caitlin Glass
- Nefetari Vivi
- Liza Marie Gonzalez
- Additional Voices
- Sam Grun
- Additional Voices
- Mark C. Guerra
- Additional Voices
- Chad Halbrook
- Additional Voices
- Nick Haley
- Additional Voices
- Matthew Ham
- Additional Voices
- Martha Harms
- Kiwi
- Clarine Harp
- Miss Monday
- Andrew Haskett
- Additional Voices
- Cleo Hayden
- Additional Voices
- Kyle Hebert
- Nefertari Cobra
- Masato Heiya
- Matsu
- Josh Hensley
- Additional Voices
- Jean-Luc Hester
- Additional Voices
- Hiroaki Hirata
- Sanji
- James Holub
- Additional Voices
- Chuck Huber
- Mohji
- Ray Hurd
- Kumacy
- Tetsu Inada
- Richie
- Jeremy Inman
- Patty
- Bradford Jackson
- Additional Voices
- Grant James
- Pagaya
- Bill Jenkins
- Narrator
- Morgan Laure
- Mozu
- Cherami Leigh
- Pepper
- Justin Locklear
- Additional Voices
- Brandon Luna
- Additional Voices
- Gregory Lush
- Additional Voices
- Seth Magill
- Additional Voices
- George Manley
- Hachi
- Masaya Matsukaze
- Gedatsu
- Robert McCollum
- Chaka
- Chris McFarland
- Additional Voices
- Mike McFarland
- Buggy
- Alex Moore
- Lola
- Ian Mead Moore
- Additional Voices
- Toshiyuki Morikawa
- Hachi
- Rob Mungle
- Igaram / Mr 8 (voice)
- Anastasia Munoz
- Additional Voices
- Kazuya Nakai
- Roronoa Zoro
- Haruhi Nanao
- Piiman
- Blake Nieman
- Additional Voices
- Kenji Nojima
- Pell
- Sean O'Connor
- Additional Voices
- Akemi Okamura
- Nami
- Ken'ichi Ono
- Dalton
- Fumiko Orikasa
- Miss Valentine
- Kate Oxley
- Carrot / Rika (voice)
- Brina Palencia
- Tony Tony Chopper
- Randy Pearlman
- Additional Voices
- Orion Pitts
- Additional Voices
- Jeff Plant
- Additional Voices
- Wendy Powell
- Negikuma Maria
- Sara Ragsdale
- Additional Voices
- Paul Giovanni Ramirez
- Additional Voices
- Dallas Reid
- Additional Voices
- Aaron Roberts
- Additional Voices
- Antimere Robinson
- Terracotta
- Richard Ross
- Additional Voices
- Chris Ryan
- Additional Voices
- Christopher Sabat
- Roronoa Zoro
- Chris Scarcia
- Additional Voices
- Patrick Seitz
- Franky
- Kyle Sharp
- Additional Voices
- Becca Shivers
- Additional Voices
- William Short
- Additional Voices
- Greg Silva
- Additional Voices
- Ian Sinclair
- Brook
- Keiichi Sonobe
- Igaram
- Marcus D. Stimac
- Dr. Hogback
- Sonny Strait
- Usopp
- Shigenori Sôya
- Mohji
- Mayumi Tanaka
- Monkey D. Luffy
- J. Michael Tatum
- Dalton
- Matt Thurston
- Additional Voices
- John Tillman
- Additional Voices
- Michael Turner
- Additional Voices
- Kihachiro Uemura
- Chaka
- Emi Uwagawa
- Rika
- Eric Vale
- Sanji
- Cristina Valenzuela
- Mao
- David Vincent
- Duval
- Jarod Warren
- Additional Voices
- Misa Watanabe
- Vivi Nefertari
- Christopher Wehkamp
- Additional Voices
- Brian Witkowicz
- Additional Voices
- Kappei Yamaguchi
- Usopp
- Yuriko Yamaguchi
- Nico Robin
- Noriko Yoshitake
- Ninjin
- Stephanie Young
- Nico Robin
- Mahito Ôba
- The Narrator
- Makiko Ômoto
- Tamanegi
- Ikue Ôtani
- Tony Tony Chopper
