- Gary Cooper
- 'Long John' Willoughby
- Barbara Stanwyck
- Ann Mitchell
- Edward Arnold
- D.B. Norton
- Walter Brennan
- The 'Colonel'
- Spring Byington
- Mrs. Mitchell
- James Gleason
- Henry Connell
- Gene Lockhart
- Mayor Lovett
- Rod La Rocque
- Ted Sheldon
- Irving Bacon
- Beany
- Regis Toomey
- Bert Hansen
- J. Farrell MacDonald
- 'Sourpuss' Smithers
- Warren Hymer
- Angelface
- Harry Holman
- Mayor Hawkins
- Andrew Tombes
- Spencer
- Pierre Watkin
- Hammett
- Stanley Andrews
- Weston
- Mitchell Lewis
- Bennett
- Charles C. Wilson
- Charlie Dawson
- Vaughan Glaser
- Governor
- Sterling Holloway
- Dan - Diner Counterman
- M.J. Frankovich
- Radio Announcer
- Knox Manning
- Radio Announcer
- John B. Hughes
- Radio Announcer
- Dorothy Andre
- American Girl
- Frank Austin
- Grubbel
- American Legion Band
- Musical Ensemble
- Evelyn Barlow
- (uncredited)
- Benny Bartlett
- Red
- Mary Benoit
- Secretary
- Max Blum
- (uncredited)
- Aldrich Bowker
- Pop Dwyer
- Sidney Bracey
- Club Member
- Fritzi Brunette
- (uncredited)
- Earle D. Bunn
- Policeman
- Nora Bush
- Citizen
- Lucia Carroll
- (uncredited)
- Glen Cavender
- (uncredited)
- Howard Chase
- Electrician
- Jack Cheatham
- Cop with Desk Sergeant
- St. Brendan's Boy Choir
- Vocal Ensemble
- Edmund Cobb
- Cop Guarding Ann
- Mildred Coles
- Secretary
- Alan Copeland
- Choirboy
- Madge Crane
- Mrs. Brewster
- Floyd Criswell
- Electrician
- Billy Curtis
- Midget
- Daisy
- The Mitchells' Dog
- Harry Davenport
- Former Bulletin Owner
- Lew Davis
- Electrician
- Vernon Dent
- (uncredited)
- Evelyn Dockson
- (uncredited)
- Ann Doran
- Mrs. Hansen
- Edward Earle
- Radio Master of Ceremonies
- Sarah Edwards
- Mrs. Hawkins
- Carl Ekberg
- Reporter
- Paul Everton
- GOP Man
- Frank Fanning
- Reporter
- Franklyn Farnum
- (uncredited)
- Eddie Fetherston
- Reporter
- Walter Findon
- (uncredited)
- Pat Flaherty
- Mike
- Bess Flowers
- Mattie
- Fern Formica
- Midget
- William Forrest
- Governor's Associate
- Charles K. French
- Fired Reporter
- Jack Gardner
- Photographer
- Inez Gay
- (uncredited)
- Ethel Gilstrom
- (uncredited)
- William Gould
- Sergeant
- Eddie Graham
- Tall Autograph Hound
- Mack Gray
- (uncredited)
- Jay Guedillio
- (uncredited)
- Alfred Hall
- Chamber of Commerce Member
- Donald Hall
- (uncredited)
- John Hamilton
- Jim
- Kenneth Harlan
- Publicity Man
- James Harrison
- (uncredited)
- Forrester Harvey
- Bum
- Edward Hearn
- Mayor's Secretary
- Oscar 'Dutch' Hendrian
- Radio Station Audience Member
- Max Hoffman Jr.
- (uncredited)
- Stuart Holmes
- (uncredited)
- John Ince
- Doctor
- Selmer Jackson
- Radio Announcer at Convention
- Frank Jaquet
- Police Desk Sergeant
- Carlotta Jelm
- Ann's Sister
- Sheldon Jett
- Man in Radio Audience
- Eddie Kane
- Wall Street Tycoon
- Edward Keane
- Relief Administrator
- Richard Kipling
- Police Commissioner
- Isabel La Mal
- Chamber of Commerce Member
- Melvin Lang
- Foreign Dignitary
- Florence Lawler
- (uncredited)
- Al Lloyd
- (uncredited)
- Anna Luther
- (uncredited)
- Hank Mann
- Eddie
- Alphonse Martell
- Foreign Dignitary
- Frank Mayo
- Attendant
- Charles McAvoy
- (uncredited)
- Mathew McCue
- Derelict
- Larry McGrath
- (uncredited)
- Joe McGuinn
- (uncredited)
- Tom McGuire
- (uncredited)
- Lafe McKee
- Mr. Delaney
- James McNamara
- Sheriff
- Edward McWade
- Joe
- Claire Meade
- (uncredited)
- George Melford
- Chamber of Commerce Member
- Frank Meredith
- Guard
- Dave Miller and His New York French Casino Band
- Musical Ensemble
- James Millican
- Photographer
- Charles R. Moore
- City Hall Janitor
- Bert Moorhouse
- Man at Stadium Rally
- Frank Moran
- (uncredited)
- Clark Morgan
- (uncredited)
- Gene Morgan
- Mug
- Jack Mower
- Guard
- Forbes Murray
- Legislator
- Gail Newbray
- Phone Operator
- Mrs. Wilfrid North
- (uncredited)
- Wedgwood Nowell
- (uncredited)
- Garry Owen
- Sign Painter
- Paul Panzer
- (uncredited)
- Edward Peil Sr.
- (uncredited)
- George Pembroke
- (uncredited)
- Bob Perry
- Delegate
- Susan Peters
- Autograph Hound
- Elsa Peterson
- (uncredited)
- Earl Pingree
- (uncredited)
- Hal Price
- (uncredited)
- Stanley Price
- (uncredited)
- John J. Richardson
- Man in Diner
- Cyril Ring
- Radio Technician
- Don Roberts
- (uncredited)
- Henry Roquemore
- Chamber of Commerce Member
- Thomas W. Ross
- (uncredited)
- Sally Sage
- (uncredited)
- Cliff Saum
- Guard
- Sada Simmons
- (uncredited)
- Russell Simpson
- (uncredited)
- Walter Soderling
- Barrington
- Wyndham Standing
- Democrat
- Edwin Stanley
- Democrat
- Vera Steadman
- (uncredited)
- Bert Stevens
- Radio Station Audience Member
- Brick Sullivan
- Policeman
- Emma Tansey
- Mrs. Delaney
- Tina Thayer
- Ann's Sister
- Cyril Thornton
- D.B.'s Butler
- Jim Thorpe
- John Doe Applicant
- Charles Trowbridge
- (uncredited)
- Don Turner
- Guard
- Guy Usher
- Bixler
- Frederik Vogeding
- (uncredited)
- Bess Wade
- (uncredited)
- Lillian West
- (uncredited)
- Bernard Wheeler
- (uncredited)
- Leo White
- (uncredited)
- Ed Williams
- (uncredited)
- Lottie Williams
- (uncredited)
- Rhoda Williams
- Minor Role
- Tom Wilson
- Diner Patron / Radio Station Audience Member (uncredited)
- Jack Wise
- Delegate
- Maris Wrixon
- Autograph Hound
