- Mark Duplass
- Charlie Brownsville
- Zoë Simpson Dean
- Casey Cook
- Paul Gordon
- Hank Morrison
- Cynthia Watros
- Allison Guthrie
- Michael Dolan
- ESA Commander David Jones
- Howe Gelb
- Shep
- Liza Weil
- Jewel
- James Kochalka
- Jackson
- Kinky Friedman
- President of the United States
- Charissa Allen
- ESA Environmental Analyst
- Elena Araoz
- ESA Operations Manager
- Nicole Atkins
- Casey's Mom
- Javier Bonafont
- Gepetto the Tailor
- Kathy Rose Center
- Reporter
- Sunhee Cho
- ESA Flight Dynamics Engineer
- Kevin Cox
- ESA Spacecraft Manager
- Don Hertzfeldt
- Reporter 2 'Reckless Conclusion'
- Robert Howell
- Secret Service Man 1
- Jonna Juul-Hansen
- The First Lady
- Nicholas Koller
- Pen Sniffin' Bum
- Jack Lee
- Reporter 1 'Mr. BBC'
- Berndt Mader
- Secret Service Man
- Amber Marslett
- Young Casey
- Geoff Marslett
- Casey's Dad
- Dave Mikol
- Reporter 3 'Isidis Planatitis'
- Spencer Parsons
- Plebe at the ESA
- Brandi Jo Perkins
- Photographer
- Garry Peters
- Pierre the Allergic Russian
- Jeremy Pollet
- Andrei the Bossy Russian
- Morgan Prine
- Younger Casey
- Jean Oliver Tchouaffe
- US Press Secretary
- Iskra Valtcheva
- ESA Software Coordinator
- Melanie West
- Reporter 4 'Indonesia'
