- Ash McGonigal
- Joe / Steve Horowitz / Old Guy / First Yokel / Nurse / Jury Foreman / Judge (voice)
- Danny Willis
- Luke / Dr. Carlos (voice)
- Carol Willis
- Luke's Mom
- Robin St. Clare
- Dr. Liz Avera / Candi / Jade Blue Afterglow (voice)
- Chris Wood
- Chief / Richard Nixon / Second Yokel / Tijuana Waiter / Times Square Dr. Carlos / Bailiff / Prison Guard (voice)
- Greg Grunberg
- Pilot Seth Norris
- Mickey Hargitay
- Crimson Executioner
- Dick Van Dyke
- Rob Petrie
- Morey Amsterdam
- Buddy Sorrell
- Rose Marie
- Sally Rogers
- Dave Dorsey
- One-Armed Guy
