- Dudley Moore
- Dr. Jack Hammond / Chris Hammond
- Kirk Cameron
- Chris Hammond / Dr. Jack Hammond
- Margaret Colin
- Ginnie Armbruster
- Catherine Hicks
- Dr. Amy Larkin
- Patrick O'Neal
- Dr. Armbruster
- Sean Astin
- Trigger
- Camille Cooper
- Lori Beaumont
- Micah Grant
- Rick Anderson
- Bill Morrison
- Uncle Earl
- Skeeter Vaughan
- Medicine Man
- Larry Sellers
- Navajo Helper
- Tami David
- Navajo Girl
- Maxine Stuart
- Phyllis
- David Wohl
- Dr. Roger Hartwood
- Michael Horton
- Dr. Mike O'Donald
- Randy Lowell
- Dr. Spellner
- Art Frankel
- Mr. Racine
- Christine Healy
- Hospital Administrator
- Mary Jane Courier
- Operating Nurse
- Debbie Zipp
- Nurse with Dying Patient
- Teresa Bowman
- Nurse with Heart Patient
- Brian Peck
- Intern with Heart Patient
- Carol Swarbrick
- Norma
- Kedric Wolfe
- Sidney - Board Member
- Robert Balderson
- Hal Gilden - Board Member
- Dakin Matthews
- Old Man Morrison
- Les Lannom
- Coach Ellis
- Lorna Hill
- Mrs. Davis
- John Stinson
- Math Teacher
- Billy Stevenson
- Biology Student
- Alexandra Kenworthy
- Janice Stenfield
- Jamison Selby
- Rick's Friend
- Lloyd Nelson
- Teacher in Hall
- John Tokatlian
- Student
- Mark McCannon
- Student
- Jan Duncan
- Student
- Armin Shimerman
- Trigger's Dad
- Kitty Swink
- Trigger's Mom
- Lisa Robins
- Bartender
- Richard Gonzales
- Paper Boy
- James Lashly
- Freemont
- Corki Grazer
- Corky
- Nancy Lenehan
- Waitress in Desert Diner
- Edwin Brecht
- Newborn at Desert Diner
- Johnathan Brecht
- Newborn at Desert Diner
- Autograph
- Rock Concert Band
- Steve Plunkett
- Rock Concert Band Autograph
- Randy Rand
- Rock Concert Band Autograph
- Steve Lynch
- Rock Concert Band Autograph
- Keni E. Richards
- Rock Concert Band Autograph
- Steve Isham
- Rock Concert Band Autograph
- Chera Bashor
- Hallway Nurse
- Bonnie Bedelia
- Lady with Gum in Hair
- Sky Bushey
- High school student
- Oscar Granquist
- Doctor
- Raymond Kohn
- Medic
- Chris Robinson
- Bobby
- Jack Starrett
- Coach Jennings
- Carol Stoddard
- Emergency Room Nurse
