- Jacob Barrett
- Self (segment "Jackass Teens")
- Jo Brown
- Superdude (segment "Superdude")
- Kristin Bunch
- Self (segment "BenJammin' Johnson")
- Jared Lee Campbell
- Self (segments "Stupid" 1-9 and "Jackass Teens") / Boss / George / Cora / Mr. Johnson (segment "You're Fired")
- Cj Carnegie
- CJ (segment "The Curse of Freddy Krueger")
- Buck Collins
- Victim (segment "Balls")
- Darren Collins
- WTF Guy (segment "Superdude")
- Larkin Collins
- Self (segment "BenJammin' Johnson")
- David Cordova
- David (segment "The Curse of Freddy Krueger")
- Matthew Crowley
- Self (segment "Jackass Teens")
- Chris Cunliffe
- FBI Agent (segment "Emo Andrew") / Victim (segment "Balls")
- James Driggers
- Self (segment "Jackass Teens")
- Preston Fletcher
- Self (segment "BenJammin' Johnson" I-II)
- Sean Foran
- Sean (segment "The Curse of Freddy Krueger")
- David Gaines
- Self (segments "Stupid" 1-9 and "Jackass Teens")
- Matthew Gaines
- Self (segments "Stupid" 1-9, "Jackass Teens", and "The Adventures of the Sockman") / Kyle Walker (segment "You're Fired") / Bebop (segment "Southern Hitman") / Bob (segment "BenJammin' Johnson" I-III)
- Maranda Gautier
- Self (segment "BenJammin' Johnson" I-II)
- Omari Geiger
- Self (segment "BenJammin' Johnson" I-II)
- Matthew Godfrey
- Self (segment "Jackass Teens" - "A Day in the life of John", and "The Adventures of the Sockman") / Victim (segment "The Mop") / Batdude (segment "Batdude")
- Zach Harms
- Boss (segment "Southern Hitman")
- Otis Haynes
- Victim (segment "Superdude")
- Jorden Hodge
- Self (segment "BenJammin' Johnson II")
- Ben Johnson
- BenJammin' Johnson (segments "BenJammin' Johnson" I-III) / Joker (segment "Batdude")
- Shannon Keifer
- Self (segment "BenJammin' Johnson II")
- Meagan Mariano
- Self (segment "BenJammin' Johnson III")
- Heber Mata
- Mugger (segment "Superdude")
- Mattfucious
- Self (segment "BenJammin' Johnson")
- Michael Messenger
- Michael (segment "The Curse of Freddy Krueger")
- Ed Parker
- Self (segment "BenJammin' Johnson")
- Elaine Perez
- Self (segment "BenJammin' Johnson" I-II)
- Chris Perkins
- Self (segment "Jackass Teens")
- Brittany Potts
- (segment "BenJammin' Johnson")
- Rachel Powell
- Self (segment "BenJammin' Johnson")
- Richard Singletary
- Mugger (segment "Superdude")
- Andrew Smith
- Emo Andrew (segment "Emo Andrew") / Victim (segment "Balls")
- Travis Smith
- Super Cracker (segment "Superdude")
- John Michael Thomas
- Self (segment "Jackass Teens" and "A Day in the life of John") / Victim (segment "The Mop")
- Cora Tillman
- Self (segment "Jackass Teens")
- Stephanie Wells
- Self (segment "BenJammin' Johnson" I and III)
- Kelli Williams
- Self (segment "BenJammin' Johnson" I-II)
- Chris Zacharias
- Mugger (segment "Superdude")
