- Jenifer Lewis
- Jackie Washington
- Tim Curry
- Edward Whatsett St. John
- T.V. Blake
- Antandra Washington (Jackie's Daughter)
- Tangie Ambrose
- Shaniqua Summers Wells (Jackie's Daughter)
- Whoopi Goldberg
- Nurse Ethyl Washington Rue Owens (Jackie's Sister)
- Robert Bailey Jr.
- Wilson Wells (Jackie's Grandson)
- Loren Freeman
- Kim (Jackie's Costume Designer)
- Tom Arnold
- Marvin Pritz (Jackie's Former Manager)
- Patti Austin
- Patti Austin (Gospel Singer at Peaches' Funeral)
- Loretta Devine
- Snookie Tate (Jackie's Childhood Friend)
- Julie Hagerty
- Pammy Dunbar (Host)
- David Hyde Pierce
- Perry (The Deaf Rehearsal Pianist)
- Kathy Najimy
- Lola Molina (Jackie's Stalker)
- Isabel Sanford
- Miss Krumes (Jackie's Play Mama)
- JoBeth Williams
- Jo Face (Jackie's Vocal Coach)
- Mary Wilson
- Vesta Crotchley (Jackie's Third Grade Teacher)
- Ski-ter Jones
- Peaches Yancy (Still Photos)
- Reynaldo Rey
- Cadillac Johnson (Retired Pimp)
- Richard Lawson
- Milkman Summers (Jackie's Ex-Husband #1)
- Lori Harmon
- Angela Scotorcio (Body Double)
- Johnny Brown
- Reverend Eustace Barnett (Pastor, Kinloch Baptist Temple)
- Alan Blumenfeld
- Ivan (Theatre Manager)
- Charles Barkley
- Charles Barkley
- Diahann Carroll
- Diahann Carroll
- Eddie Cibrian
- Eddie Cibrian
- Jackie Collins
- Jackie Collins
- Don Cornelius
- Don Cornelius
- Taylor Dayne
- Taylor Dayne
- Melissa Etheridge
- Melissa Etheridge
- Kathy Griffin
- Kathy Griffin
- Sean Hayes
- Sean Hayes
- Ricki Lake
- Ricki Lake
- Howie Mandel
- Howie Mandel
- Camryn Manheim
- Camryn Manheim
- Penny Marshall
- Penny Marshall
- Bette Midler
- Bette Midler
- Liza Minnelli
- Liza Minnelli
- Rosie O'Donnell
- Rosie O'Donnell
- Dolly Parton
- Dolly Parton
- Donna Pescow
- Donna Pescow
- Chris Rock
- Chris Rock
- Eva Marie Saint
- Eva Marie Saint
- Grace Slick
- Grace Slick
- Robert Townsend
- Robert Townsend
- Bruce Vilanch
- Bruce Vilanch
- Robert Cesario
- Anthony (Paranoid Fan)
- Dee Freeman
- Tired Woman
- Freez Luv
- Larry (Die-Hard Fan)
- Cynthia Palmer
- Doris (Confused Fan)
- Ashli Adams
- Inquisitive Kid
- David Alexander
- Stage Foreman
- Gary Clancy
- Sound Man / St. John's Crew
- John Cook
- Dancer
- Joey Gaynor
- Camera Man / St. John's Crew
- Jason Kravits
- Wimpy Bald Man
- Rudy Ray Moore
- Bad Guy (Coco Movie)
- Art Palmer
- Dancer
- Regan Patno
- Dancer
- Kyla Pratt
- Little Jackie Washington
- Lance Taylor
- Hostage
- Jerald Vincent
- Dancer
- Angela Wright
- Church Lady
- Sophia Santi
- Anti-Fur Protester #1
- Khyle Armour Waters
- Anti-Fur Protester #2
- Suzanne Suter
- Anti-Fur Protester #3
- Elaine Ward
- Anti-Fur Protester #4
- Brian Nahas
- Anti-Fur Protester #5
- Julia Dion
- Anti-Fur Protester #6
- Scot Zeller
- Thin Love Goddess Dancer #1
- Brian Elfand
- Thin Love Goddess Dancer #2
- Terrell Clayton
- Musician #1
- Gene Ryals
- Musician #2
- Ski Carr
- Bass Player
- Rae Ritke
- Reporter #1
- Terrence Flack
- Hospital Reporter
- Tony Brubaker
- Fight Biker
- Danny Epper
- Fight Biker
- Bennie Moore
- Fight Biker
- Manny Perry
- Fight Biker
- Scott L. Schwartz
- Fight Biker
- Craig Shugart
- Fight Biker
- Jeanne Marie Spicuzza
- 'Yield' Fan
