- John Wayne
- Capt. Dooley
- Lloyd Nolan
- Captain Stutz
- Walter Abel
- Col. Fuller
- James Arness
- Mac McMullen
- Andy Devine
- Willie Moon
- Allyn Joslyn
- J.H. Handy
- Jimmy Lydon
- Murray
- Harry Carey Jr.
- Ralph Hunt
- Hal Baylor
- Stankowski
- Sean McClory
- Frank Lovatt
- Wally Cassell
- D'Annunzia
- Gordon Jones
- Walrus
- Frank Fenton
- Capt. Turner
- Robert Keys
- Maj. Ditson
- Sumner Getchell
- Lt. Cord
- Regis Toomey
- Sgt. Harper
- Paul Fix
- Wally Miller
- Jim Dugan
- Gidley
- George Chandler
- Rene
- Louis Jean Heydt
- Fitch
- Bob Steele
- Wilson
- Darryl Hickman
- Swanson
- Mike Connors
- Gainer
- Carl 'Alfalfa' Switzer
- Sonny Hopper
- Cass Gidley
- Stannish
- Herbert Anderson
- Breezy
- Anthony De Mario
- Ogden
- Billy Lee Aimone
- Boy
- Dawn Bender
- Murray's Wife
- Gene Coogan
- Stutz's Navigator
- Ann Doran
- Moon's Wife
- Ed Fury
- Server in Officer's Mess
- John Indrisano
- Mechanic
- Tom Irish
- Dusty - McMullen's Co-Pilot
- Billy Lunde
- Boy
- Fess Parker
- Fitch's Co-Pilot
- Richard Walsh
- (uncredited)
- Michael Wellman
- Mike Moon
- Tim Wellman
- Jim Moon
- William A. Wellman
- Narrator
- Phyllis Winger
- Margaret - Girl in Flashback
