- Charles Boyer
- Paul Dumond
- Jean Arthur
- Irene Vail
- Leo Carrillo
- Cesare
- Colin Clive
- Bruce Vail
- Ivan Lebedeff
- Michael Brovsky
- George Meeker
- Norton
- Lucien Prival
- Private Detective
- George Davis
- Maestro
- Bobby Barber
- Paul
- Phyllis Barry
- Undetermined Secondary Role
- Joseph E. Bernard
- Headwaiter at Victor's
- Jeanne Blanche
- Undetermined Secondary Role
- Barlowe Borland
- Clumsy Waiter at Cesare's
- Harvey Clark
- Victor
- Dora Clement
- Dowager
- Adrienne D'Ambricourt
- French Woman
- Harry Depp
- Waiting Customer at Victor's
- Edward Earle
- Ship's Officer Talking to Captain Alden
- Gloria Eaton
- Undetermined Secondary Role
- Franklyn Farnum
- Waiter
- Byron Foulger
- Vail Employee Reading from Newspaper
- Roger Gray
- Detective Finding Irene
- Tim Holt
- S.O.S. Radio Operator
- George Humbert
- Ship's Chef
- Payne B. Johnson
- Boy on Ship
- Jeannette Kerner
- Hat Check Girl
- Tetsu Komai
- SOS Radio Operator
- Rollo Lloyd
- Reservations Man at Victor's
- John Marston
- Captain Alden
- Louis Mercier
- Cab Driver
- Martha Merrill
- Employee at Victor's
- Helene Millard
- Mrs. Vaughan
- Carlyle Moore Jr.
- Wireless Operator
- Jack Mulhall
- Waiter
- David Newell
- Passenger with Lifejacket
- Barry Norton
- Undetermined Secondary Role
- Dennis O'Keefe
- Restaurant Patron
- Robert Parrish
- Ship Passenger
- Russ Powell
- Chef with Mustache
- June Preston
- Little Girl with Dog
- Georges Renavent
- Inspector Millard
- Jack Richardson
- Wireless Operator
- Tom Ricketts
- Old Man Getting in Lifeboat
- James Sheridan
- Waiter
- Adele St. Maur
- Hotel Maid
- William Stack
- Vail's Attorney
- Amzie Strickland
- Restaurant Patron
- Pierre Watkin
- Commodore Eldridge
- Charles Williams
- Room Service Waiter on Ship
