- Billy Crystal
- Charlie Burnz
- Chad Jennings
- Police Officer
- Dierdre Friel
- Marge
- Alex Brightman
- Justin
- Matthew Broussard
- Roger
- Max Gordon Moore
- Brad
- Susan Pourfar
- Paula
- Gianmarco Soresi
- Lenny
- Sarah Stiles
- Sarah
- Joanna Adler
- Director
- Justin Linville
- Wallace
- Brandon Uranowitz
- Gary
- Andrew Durand
- Darrell
- Tiffany Haddish
- Emma Payge
- Zuhdi Boueri
- Waiter
- Lisann Valentin
- Paramedic
- Tijuana Ricks
- Nurse
- Andy Grotelueschen
- Doctor
- Josh Lamon
- Pharmacist
- Penn Badgley
- Rex
- Janice Crystal
- Gram
- Shiloh Verrico
- Young Francine
- Drew Levy
- Young Rex
- Philippe Arroyo
- Locker Room Attendant
- Audrey Hsieh
- Lindsay
- Chayim Frenkel
- Rabbi Teplitz
- Laura Benanti
- Francine
- Anna Deavere Smith
- Dr. Vidor
- Sharon Stone
- Sharon Stone / Iris
- Kevin Kline
- Kevin Kline / Ben
- Bob Costas
- Bob Costas
- Barry Levinson
- Barry Levinson
- Louisa Krause
- Carrie
- Charlie Rosen
- Bass Player
- Marques Walls
- Drummer
- Nyambi Nyambi
- Dwayne
- Derrick Williams
- Construction Worker
- Spencer Barnes
- Delivery Person
- Steven Castillo
- Museum Security Person
- Peter Grosz
- Doctor Joe
- Fred Bernstein
- Cub Scout Leader
- Declan Manning
- Cub Scout
- Charlie Pollock
- Larry
- Clay Singer
- Bat Mitzvah DJ
- Itzhak Perlman
- Itzhak Perlman
- Alan Zweibel
- Al (Cue Card Guy)
- Sari Zweibel
- Audience Member #1
- Tamiz U. Rezvi
- Audience Member #2
- Tony Naumovski
- Uber Driver
- Giovanni Michael Abate
- Cub Scout
- Amanda Abbruzze
- Friend at Bat Mitzvah
- Marshall Axt
- Bat Mitzvah Guest
- Chris Cafero
- Warm-Up Guy
- Aidan Christman
- Bat Mitzvah Guest
- Dominic DiGravio
- Cub Scout
- Grayson Eddey
- Harry
- Kathryn Grace
- Lindsay's Friend
- James C.B. Gray
- Construction worker
- Michael Jones
- Mike
- Nicholas LaRocco
- Bat Mitzvah Kid
- Rebecca Merle
- Bat Mitzvah Family Dancer
- Mark Mindek
- Man with Toupee
- Cindy Motz
- Band Member
- Madeline Faye Santoriello
- Bat Mitzvah Guest
- Laurie Sheppard
- Audience Member
- Hank Strong
- Patient
