- Meryl Streep
- Rachel
- Jack Nicholson
- Mark
- Jeff Daniels
- Richard
- Maureen Stapleton
- Vera
- Stockard Channing
- Julie
- Richard Masur
- Arthur
- Catherine O'Hara
- Betty
- Steven Hill
- Rachel's Father
- Milos Forman
- Dmitri
- Mamie Gummer
- Annie
- Karen Akers
- Thelma Rice
- Aida Linares
- Juanita
- Anna Maria Horsford
- Della
- Ron McLarty
- Detective O'Brien
- Kenneth Welsh
- Dr. Appel
- Kevin Spacey
- Subway Thief
- Mercedes Ruehl
- Eve
- Joanna Gleason
- Diana
- R.S. Thomas
- Dan
- Jack Gilpin
- Ellis
- Christian Clemenson
- Sidney
- John Wood
- British Moderator
- Sidney Armus
- Jeweler
- Yakov Smirnoff
- Contractor Laszlo
- Caroline Aaron
- Judith
- Lela Ivey
- Hairdresser
- Tracey Jackson
- Hairdresser's Friend
- Libby Titus
- Rachel's Sister
- Angela Pietropinto
- Hospital Receptionist
- Cynthia O'Neal
- Magazine Colleague
- Susan Forristal
- Magazine Colleague
- Dana Ivey
- Wedding Speaker
- John Rothman
- Jonathan Rice
- Elijah Lindsay
- Anesthetist
- Jack Neam
- Butcher
- Kim Fertman
- Arthur & Julie's Daughter
- Salem Ludwig
- Judge
- Patricia Falkenhain
- Dinner Party Hostess
- Margaret Thomson
- Irritated Wedding Guest
- Charles Denny
- Dinner Party Guest
- Gregg Almquist
- Dinner Party Guest
- Garrison Lane
- Dinner Party Guest
- Ryan Hilliard
- Dinner Party Guest
- Dana Streep
- Dinner Party Guest
- Mary Streep
- Dinner Party Guest
- Cyrilla Dorn
- Dinner Party Guest
- May Pang
- Dinner Party Guest
- Michael Regan
- Father of the Bride
- Ari M. Roussimoff
- Workman
- Luther Rucker
- Workman
- Gary Jones
- Waiter in Opening Sequence
- Jack Larravide
- Extra
- Natasha Lyonne
- Rachel's Niece
- Jeff Mazzola
- Flower Delivery Guy
- Jorge Pupo
- Subway Rider
- Grant Harper Reid
- Man in Maternity Scene
- Carlotta Schock
- Dinner Guest
- Tony Shalhoub
- Airplane Passenger
