- Wesley Snipes
- Marcus
- Aunjanue Ellis-Taylor
- Rachel
- Zoë Bell
- Floria
- Ernie Hudson
- Clarence
- Quinn Duffy
- Redvale
- Gary Daniels
- Zander
- Robert Davi
- Smith
- Eyad Elbitar
- Driver
- Simon Rhee
- Agent #1
- Ho-Sung Pak
- Agent #2 / Big Mental
- Efka Kvaraciejus
- Agent #4
- Carl Anthony Nespoli
- Agent #4 / Assassin #7
- Don Richard
- Agent #5 / Assassin #8
- Jeff Galpin
- Assassin #1
- Vladimir Tevlovski
- Assassin #2
- Ele Bardha
- Security Guy #1 / Security Guard #1
- Craig Gubert
- Security Guy #2 / Security Guard #2
- George Pogacich
- Mental Patient #1
- Rory Mallon
- Mental Patient #2
- Banzai Vitale
- Mental Patient #3
- Alex Wisz
- Mental Patient #5
- Jaime Moyer
- Floor Nurse
- Ronald Clark
- Train Conductor (Old Man)
- Vanessa Vander Pluym
- Worker
- Dailyn Matthews
- Nurse
- Marie Fink
- ICU Nurse
- Julissa Deleon
- Reception Nurse
- Alex Safi
- Arms Dealer
- Iris Frank
- Girl
- Michael Maurice
- Dietrich
- Angelea Jenkins
- ER Orderly
- John Manfredi
- Robbins
- LaDon Drummond
- Jane
- Greg Trzaskoma
- Redvale Reception Clerk
- Brian Christensen
- Redvale Security Guard #1
- Danny Ray Cook
- Redvale Security Guard #3
- Patrick Potochick
- Redvale Security Guard #4
- Lennox Brown
- Redvale Clerk
- Darcy Leutzinger
- Police Team Leader
- Frank Zieger
- Policeman #1
- Denney Pierce
- Motocycle Assassin / Sedan Driver
- Dan Lemieux
- Alley Body Guard #1
- Scott Philyaw
- Alley Body Guard #2
- Nick Hermz
- Alley Body Gaurd #3
- Gary Baxley
- White Van Driver
- Stacie Mitchell
- Annie
- Ron Balicki
- Jimmy
- Benjamin Brennan
- Bum
- Jennifer Lynn Bryant
- Nurse
- Dennis Budziszewski
- Bum
- Keith Cameron
- Policeman #2
- John Dickerson
- Cop
- Richard Goteri
- The Visitor
- Eric Ian
- The Informant
- Dave Kilgore
- Psych Ward Patient
- Joshua McCarthy
- Patient
- Dennis McDermott
- Mental Patient
- Michael Mili
- (uncredited)
- Robert Oppel
- Mental Lou
- Todd Rader
- Security Guard, Homeless Man
- Morris Lee Sullivan
- Anesthesiologist
