- Robert Montgomery
- Paul Porter aka Stephen Blaine
- Madge Evans
- Letty Morris
- Ted Healy
- Hector Withington, Jr.
- Nat Pendleton
- Legs Caffey
- C. Henry Gordon
- Detective Daly
- Ruth Selwyn
- Babe Callahan
- Larry Fine
- One of The Three Julians
- Moe Howard
- One of The Three Julians
- Curly Howard
- One of The Three Julians
- Wade Boteler
- Cop
- Walter Brennan
- Second Bus Driver
- Buster Brodie
- Member of the Audience
- Don Brodie
- Lefty
- James Burke
- Joe Cobb
- James P. Burtis
- Bus Mechanic
- Heinie Conklin
- Man at Bus with Hector
- Ray Cooke
- Bellboy
- Nell Craig
- Cashier at Altoona Cafe
- Richard Cramer
- Police Lieutenant
- Louise Emmons
- Pittsburgh Bus Station Newspaper Hawker
- Edith Fellows
- Girl on School Bus
- Edward Gargan
- Policeman
- Sumner Getchell
- Well-Wisher at Bus Station
- Jack Gray
- Man
- Harrison Greene
- Hector's Drunken Friend
- Sherry Hall
- Bus Station Clerk
- Virginia Hammond
- Straight-Laced Bus Passenger
- Edward Hearn
- Detective
- Ben Hendricks Jr.
- Steve
- Al Hill
- Joe
- DeWitt Jennings
- Warden
- Milton Kibbee
- Hector's Drunken Friend
- Walter Long
- Prison Guard
- Wilbur Mack
- Theatre Manager
- Margaret Mann
- Blind Man's Wife
- Sam McDaniel
- Station Attendant Washing Floor
- Dad Mills
- Blind Man
- Charles R. Moore
- Porter
- Inez Palange
- Maria
- John Qualen
- Distressed Parent
- Constantine Romanoff
- Prison Guard
- Syd Saylor
- Third Bus Driver
- Frank Sheridan
- Police Chief
- Akim Tamiroff
- Deaf-Mute Bus Passenger
- Harry Tenbrook
- Policeman
- Fred 'Snowflake' Toones
- Man Driving During Escape
- Maidel Turner
- Little Boy's Mother
- Bobby Watson
- Eddie
- Delmar Watson
- Tommy
- Leo White
- Bus Passenger
