- Meredith Baxter
- Â Elyse Keaton / ... 172 episodes, 1982-1989
- Michael Gross
- Â Steven Keaton / ... 172 episodes, 1982-1989
- Michael J. Fox
- Â Alex P. Keaton 172 episodes, 1982-1989
- Justine Bateman
- Â Mallory Keaton / ... 172 episodes, 1982-1989
- Tina Yothers
- Â Jennifer Keaton / ... 172 episodes, 1982-1989
- Brian Bonsall
- Â Andrew 'Andy' Keaton 75 episodes, 1986-1989
- Marc Price
- Â Irwin 'Skippy' Handelman / ... 54 episodes, 1982-1989
- Scott Valentine
- Â Nick Moore 45 episodes, 1985-1989
- Courteney Cox
- Â Lauren Miller 20 episodes, 1987-1989
- Tracy Pollan
- Â Ellen Reed 15 episodes, 1985-1989
- John Hancock
- Â Gus Thompson 7 episodes, 1983-1989
- Terry Wills
- Â Dr. Schulte / ... 7 episodes, 1983-1989
- Robert Schanche
- Â Robert / ... 9 episodes, 1983-1989
- Alan Blumenfeld
- Â George Bellack / ... 6 episodes, 1984-1987
- Enid Kent
- Â Phyllis Evans / ... 6 episodes, 1982-1988
- Robert Costanzo
- Â Andrew the Waiter / ... 5 episodes, 1984-1987
- John Petlock
- Â Ted Waterman / ... 5 episodes, 1982-1986
- Norman Parker
- Â Robert Keaton 5 episodes, 1985-1987
- John Dukakis
- Â Jeff Wakefield 4 episodes, 1983-1984
- David Wohl
- Â Oscar - 'Peter Good Vibes' / ... 4 episodes, 1985-1988
- Michael David Wright
- Â Young Steven Keaton / ... 4 episodes, 1984-1988
- Ben Piazza
- Â Mr. Wertz / ... 4 episodes, 1984-1987
- Bunny Summers
- Â Barbara / ... 4 episodes, 1983-1988
- Denise D'Amico
- Â Customer #2 / ... 4 episodes, 1985-1989
- Tom Hanks
- Â Ned Donnelly 3 episodes, 1983-1984
- John Putch
- Â Neil / ... 4 episodes, 1982-1986
- Melinda Culea
- Â Rebecca Ryan 3 episodes, 1986-1987
- Timothy Busfield
- Â Doug / ... 3 episodes, 1984-1986
- Matthew Faison
- Â Dr. Skip Williamson / ... 3 episodes, 1985-1987
- James N. Hamilton
- Â Bellhop / ... 3 episodes, 1985-1987
- Margaret Marx
- Â Young Elyse Donnelly / ... 3 episodes, 1986-1988
- Jane Adams
- Â Marty Brodie / ... 3 episodes, 1987-1989
- Philip Baker Hall
- Â Dr. Harrison 3 episodes, 1988
- Raymond Singer
- Â Buffaloed Bill / ... 3 episodes, 1986-1988
- Walter Olkewicz
- Â Bill Channing / ... 2 episodes, 1984-1987
- Priscilla Morrill
- Â Kate / ... 2 episodes, 1982-1984
- Sal Viscuso
- Â Richard Grasso / ... 2 episodes, 1982-1984
- Belita Moreno
- Â Bernice / ... 2 episodes, 1983-1986
- Mary Farrell
- Â Carol Mannings / ... 2 episodes, 1983-1985
- Richard Venture
- Â Agent Bert Carlyle 2 episodes, 1983
- Jason Naylor
- Â Simon Wickerson 2 episodes, 1987-1989
- Tammy Lauren
- Â Marilyn Keaton 2 episodes, 1987
- Julie Cobb
- Â Maureen Keaton 2 episodes, 1987
- Dan Hedaya
- Â Joe Moore 4 episodes, 1988-1989
- Philip Sterling
- Â Mr. Winkler 2 episodes, 1982-1984
- Jay Tarses
- Â Ron Davis 2 episodes, 1982-1983
- Brooke Alderson
- Â Suzanne Davis 2 episodes, 1982-1983
- Daphne Zuniga
- Â Rachel Miller 2 episodes, 1984
- Sam Whipple
- Â Bill / ... 2 episodes, 1984
- Suzanne Snyder
- Â Tricia Armstrong 2 episodes, 1985
- Rick Podell
- Â Jackie Jackerman 2 episodes, 1985
- Christina Pickles
- Â Mrs. Ruth Hobart 2 episodes, 1988
- Lois De Banzie
- Â Mrs. Rose Handelman / ... 3 episodes, 1984-1989
- Michael Zorek
- Â Flaum 2 episodes, 1984-1986
- Jeff Joseph
- Â James Jarrett 2 episodes, 1984-1985
- Wendel Meldrum
- Â Kathy Brady 2 episodes, 1987
- Blake Sennett
- Â Jonathan Keaton 2 episodes, 1987
- Fess 'Reg' Reynolds
- Â Reggie 2 episodes, 1987
- Bibi Besch
- Â Dr. Hewitt 2 episodes, 1988
- Earl Boen
- Â Ed Barker / ... 4 episodes, 1983-1987
- Geena Davis
- Â Karen Nicholson 3 episodes, 1984-1986
- David Paymer
- Â Larry Harris 2 episodes, 1985
- Jack Blessing
- Â Leonard 2 episodes, 1985
- Sonia Curtis
- Â Amy Sussman 2 episodes, 1987
- Rosalind Cash
- Â Maya Thompson 2 episodes, 1989
- Chris Hebert
- Â Young Alex 2 episodes, 1982-1983
- John Hostetter
- Â Stage Manager / ... 2 episodes, 1984-1987
- Masakio
- Â Chester 2 episodes, 1987
- Christian Clemenson
- Â Mr. Flaherty 2 episodes, 1988
- Raleigh Bond
- Â Harry Handelman / ... 3 episodes, 1984-1989
- Karlene Crockett
- Â Marge 2 episodes, 1985
- Julie Fulton
- Â Suzie Harris 2 episodes, 1985
- Anne Bellamy
- Â Boardwoman / ... 2 episodes, 1987-1989
- Keith Amos
- Â Michael Thompson 2 episodes, 1989
- Jeff Cohen
- Â Dougie Barker / ... 3 episodes, 1984-1987
- Bernadette Birkett
- Â Carol / ... 2 episodes, 1985-1988
- Joseph Gordon-Levitt
- Â Dougie 2 episodes, 1988
- Rachel Jacobs
- Â Jill 2 episodes, 1988
- Richard Kuss
- Â Mr. Meyers 2 episodes, 1988
- Kevin Dunn
- Â Bob Dunphy / ... 2 episodes, 1988-1989
- Carolyn Mignini
- Â Peggy Vincent 2 episodes, 1988
- Ron Karabatsos
- Â Bud Carlson 3 episodes, 1985-1987
- Mark L. Taylor
- Â Phil 2 episodes, 1989
- Baillie Gerstein
- Â Mrs. Hummier / ... 2 episodes, 1988-1989
- Betsy Randle
- Â Nancy 2 episodes, 1989
- Edward Edwards
- Â Mr. Rubin Tedesco / ... 2 episodes, 1983-1987
- Crispin Glover
- Â Doug 2 episodes, 1984-1986
- Tracy Nelson
- Â Deena / ... 5 episodes, 1984-1989
- Amy Lynne
- Â Chrissy Nardino 2 episodes, 1987
- Heather Hobbs
- Â Stacie Connors 2 episodes, 1987
- Richard McGonagle
- Â Brother Timothy / ... 1 episode, 1987-1989
- Stephanie Dizon
- Â Holly 2 episodes, 1987
- Billy Morrissette
- Â Paul Corman / ... 1 episode, 1988-1989
- Alyson Croft
- Â Brooke 2 episodes, 1987
- Nicole Nourmand
- Â Beth Hooper 2 episodes, 1987
- Niall Gartlan
- Â Brett McKenzie 2 episodes, 1987
- Gino De Mauro
- Â Zack Phillips 2 episodes, 1987
- John Randolph
- Â Jake Keaton 1 episode, 1982
- Dick Sargent
- Â Charlie 1 episode, 1982
- Lee Montgomery
- Â Eric Morrison 1 episode, 1982
- Jack Riley
- Â Earl Quigley 1 episode, 1982
- Amy Steel
- Â Stephanie Brooks 1 episode, 1982
- Peter Jurasik
- Â Max Brown 1 episode, 1982
- Cindy Fisher
- Â Kimberly Blanton 1 episode, 1982
- David Spielberg
- Â Arthur Press 1 episode, 1982
- Cristen Kauffman
- Â Cindy Sullivan 1 episode, 1982
- Jack Somack
- Â Mr. Adler 1 episode, 1982
- Andrew J. Lederer
- Â Howie 1 episode, 1982
- Jeremy Schoenberg
- Â Justin Perkins 1 episode, 1982
- Judith Light
- Â Stacey Hughes 1 episode, 1983
- Talia Balsam
- Â Carrie Newman 1 episode, 1983
- Deborah Foreman
- Â Mary Catherine Robbins 1 episode, 1983
- Carolyn Seymour
- Â Lorraine Ferrar 2 episodes, 1983-1987
- Lisa Lucas
- Â Sherry Marshall 1 episode, 1983
- Philip Charles MacKenzie
- Â Dan Matthews 2 episodes, 1983-1986
- James Sutorius
- Â Richard 1 episode, 1983
- Kaleena Kiff
- Â Young Mallory 1 episode, 1983
- Frank Dent
- Â Ed Hanson 3 episodes, 1983-1987
- Gene Akutagawa
- Â Ming Nguyen 1 episode, 1983
- Jami Gertz
- Â Jocelyn Clark 1 episode, 1984
- Gail Strickland
- Â Dorothy Canell 5 episodes, 1984-1989
- Nancy Parsons
- Â Nurse 1 episode, 1984
- Michael McGuire
- Â Professor Bronski 1 episode, 1984
- Matthew Barry
- Â Scott 4 episodes, 1984-1987
- Thomas Byrd
- Â Rick Harmon 1 episode, 1984
- Arthur Taxier
- Â The Dealer 3 episodes, 1984-1989
- Nancy Everhard
- Â Robin Green 1 episode, 1985
- Robert Desiderio
- Â Richard 'Richie' Schofield 1 episode, 1985
- Anne Seymour
- Â May Keaton 1 episode, 1985
- Steven Peterman
- Â Man in Restaurant 1 episode, 1985
- Isabelle Walker
- Â Donna Barros 1 episode, 1985
- Miriam Flynn
- Â Mrs. Carpenter 2 episodes, 1986-1987
- Danielle von Zerneck
- Â June 1 episode, 1987
- Howard Renensland
- Â Bernie Packer 1 episode, 1987
- Betsy Russell
- Â The Girl 1 episode, 1982
- Julie Payne
- Â Lynn Sullivan 1 episode, 1982
- Charles Levin
- Â Dr. 'Crazy Larry' Waxman 1 episode, 1982
- Pat McNamara
- Â Officer Becker 1 episode, 1982
- Susan Bay Nimoy
- Â Julia Newman 1 episode, 1983
- Anne Haney
- Â Mrs. Matthews 1 episode, 1983
- John McCook
- Â Tuxedo Man 3 episodes, 1983-1987
- Moosie Drier
- Â Arnie 1 episode, 1983
- Tanya Fenmore
- Â Arlene 1 episode, 1983
- Irene Yah-Ling Sun
- Â Tanly Nguyen 1 episode, 1983
- Donna McKechnie
- Â Cynthia 1 episode, 1983
- Robin Evans
- Â The Girl 1 episode, 1983
- Hannah Cutrona
- Â Melissa Ferrar 1 episode, 1983
- Bob Tzudiker
- Â Mr. Needham 1 episode, 1983
- Margaret Fitzgerald
- Â Mary Beth McCallister 1 episode, 1983
- Zeke Zacarro
- Â Guido 1 episode, 1983
- Robert Pine
- Â Dean Ian McCall 1 episode, 1984
- Michelle Meyrink
- Â Jane 3 episodes, 1984-1989
- Rebecca Balding
- Â Karen Banks 1 episode, 1984
- James Karen
- Â Philip 1 episode, 1984
- Marsha Warfield
- Â Doris Bradshaw 1 episode, 1984
- Doris Belack
- Â Mrs. Willis 1 episode, 1984
- Lenora May
- Â Margo 1 episode, 1984
- Seth Jaffe
- Â The Pit Boss 3 episodes, 1984-1989
- Milt Oberman
- Â Andy 1 episode, 1984
- Duncan Ross
- Â Dean Memminger 1 episode, 1984
- Jane Alden
- Â Ms. Janice Worthy 1 episode, 1984
- Richard Morof
- Â The Waiter 3 episodes, 1984-1987
- River Phoenix
- Â Eugene Forbes 1 episode, 1985
- Noah Hathaway
- Â Adam Galardner 1 episode, 1985
- Adam Carl
- Â Young Steven Keaton 1 episode, 1985
- John Scott Clough
- Â David 3 episodes, 1985-1989
- Edith Atwater
- Â Gertrude 'Trudy' Harris 1 episode, 1985
- Radha Delamarter
- Â Woman in Restaurant 1 episode, 1985
- Haviland Morris
- Â Sharon McElroy 1 episode, 1986
- Ronny Cox
- Â Franklin Reed 1 episode, 1986
- Tony Carreiro
- Â Terry Bridgeman 1 episode, 1986
- Lisa Sloan
- Â Professor Marshall 1 episode, 1986
- Robin Morse
- Â Allison King 1 episode, 1986
- Albert Macklin
- Â Ivan Rozmirovich 1 episode, 1986
- Sanford Jensen
- Â Matt Gilbert 2 episodes, 1986-1987
- Dion Rottman
- Â Chuck 1 episode, 1986
- Karen Landry
- Â Michele 1 episode, 1987
- Bill Allen
- Â Roger Sloate 1 episode, 1987
- Jack Heller
- Â Chaim 1 episode, 1987
- Barry Jenner
- Â David Campbell 1 episode, 1988
- Constance McCashin
- Â Evelyn Mitchum 1 episode, 1988
- Granville Van Dusen
- Â Mr. Carter 1 episode, 1988
- Kaylan Romero
- Â Rocco 1 episode, 1988
- Douglas Seale
- Â Joseph Simmons 1 episode, 1989
- Byron Thames
- Â Josh Wakefield 1 episode, 1989
- Tom Isbell
- Â Dr. Austin 1 episode, 1989
- Barry Heins
- Â Mr. Hilgenburg 1 episode, 1989
- Christine Jansen
- Â Jessica Foster 1 episode, 1989
- Larry Hankin
- Â Walter 1 episode, 1982
- Randy Lowell
- Â Bobby Cahill 1 episode, 1982
- Mari Gorman
- Â Nurse 1 episode, 1982
- Toni Sawyer
- Â Mrs. Emily Blanton 1 episode, 1982
- David Faustino
- Â Keith Bailey 1 episode, 1983
- Sarah Abrell
- Â Heather 1 episode, 1983
- Michael Spound
- Â Neil 1 episode, 1983
- Chris Nash
- Â Victor 1 episode, 1983
- Kerry Noonan
- Â Mary Margaret Dunne 1 episode, 1983
- Molly David
- Â Mrs. Jones 1 episode, 1983
- Farrin Jacobs
- Â Jessica 1 episode, 1983
- Tate Donovan
- Â Clancy 1 episode, 1984
- Anne Ramsey
- Â Mrs. Warfield 1 episode, 1984
- Joshua John Miller
- Â Kenneth 1 episode, 1984
- Frances Bay
- Â Mrs. Florence Menlo 1 episode, 1984
- Alison La Placa
- Â Barbara 1 episode, 1984
- Susan Isaacs
- Â Linda 1 episode, 1984
- Shawn Schepps
- Â Darlene Driscoll 1 episode, 1984
- Eileen Seeley
- Â Roxanne 1 episode, 1984
- Barry Sobel
- Â Petey Gordon 1 episode, 1984
- Charles Walker
- Â The Waiter 1 episode, 1984
- Michael Currie
- Â Mr. Halifax 1 episode, 1984
- Garn Stephens
- Â Elizabeth Davidson 1 episode, 1984
- James Cromwell
- Â John Hancock 1 episode, 1985
- Martha Plimpton
- Â Jessie Blake 1 episode, 1985
- Danny Nucci
- Â Rick 1 episode, 1985
- Pamela Springsteen
- Â Gail 1 episode, 1985
- Molly Cheek
- Â Frances Wilder 1 episode, 1985
- Wyatt Knight
- Â William 1 episode, 1985
- Bruce Jarchow
- Â Ted 1 episode, 1985
- Peter Hobbs
- Â Professor Walter Jenkins 1 episode, 1985
- Kurt Smildsin
- Â Waiter 1 episode, 1985
- Judson Allen
- Â Jack 1 episode, 1985
- Terry Farrell
- Â Liz Obeck 1 episode, 1986
- Amy O'Neill
- Â Brenda 1 episode, 1986
- Julie Harris
- Â Margaret 1 episode, 1986
- Jennifer Salt
- Â Mrs. Kluger 2 episodes, 1986-1987
- Harvey Jason
- Â Pierre 1 episode, 1986
- Alex Henteloff
- Â Coach 1 episode, 1986
- John Ingle
- Â Justice of the Peace 3 episodes, 1986-1989
- Amy Benedict
- Â Eve Kimball 1 episode, 1986
- Anne Marie McEvoy
- Â Alice 2 episodes, 1986-1987
- Tom Bresnahan
- Â Brian Elliott 1 episode, 1986
- Allyson Rice
- Â Becky 1 episode, 1986
- Suzanne Lederer
- Â Dr. Sylvia 1 episode, 1986
- Bruce Toms
- Â Gregg 1 episode, 1986
- Christina Applegate
- Â Kitten 1 episode, 1987
- Campbell Scott
- Â Eric Matthews 1 episode, 1987
- Brian McNamara
- Â Greg 1 episode, 1987
- Gloria Gifford
- Â Akila 1 episode, 1987
- J. Anthony Crane
- Â Roger 1 episode, 1987
- Laura Leigh Hughes
- Â Cindy 1 episode, 1987
- Eli Marder
- Â Tracy 1 episode, 1987
- Julia Louis-Dreyfus
- Â Susan 'Raindrop' White Esq. 1 episode, 1988
- Terri Hanauer
- Â Miss Metcalf 1 episode, 1988
- Rod McCary
- Â Dr. Jeff Cooper - 'Randolph' 2 episodes, 1987-1988
- Debra Engle
- Â Jamie Carter 1 episode, 1988
- Jeff Perry
- Â David Simmons 1 episode, 1989
- John Marshall Jones
- Â Sgt. Tom Davis 1 episode, 1989
- Jaclyn Bernstein
- Â Marla 1 episode, 1989
- Carol Mansell
- Â Woman with Cats 1 episode, 1989
- Ethel Ayler
- Â Ms. Daniels 1 episode, 1989
- Mary Jackson
- Â Edna 1 episode, 1982
- Bruce French
- Â Dr. Rogers 1 episode, 1982
- Maurice Marsac
- Â Roger 1 episode, 1982
- Alan Haufrect
- Â Customer #1 1 episode, 1982
- Jack O'Leary
- Â The Guard 1 episode, 1982
- Woody Eney
- Â Rob Peterson 1 episode, 1983
- Eve Roberts
- Â Mrs. Marin 1 episode, 1983
- Kelly Ann Conn
- Â Sherry 1 episode, 1983
- Isabell O'Connor
- Â Waitress 1 episode, 1983
- John Gallogly
- Â Head Judge 1 episode, 1983
- Bob O'Donnell
- Â Chuck 1 episode, 1983
- Billy Campbell
- Â Lyle 1 episode, 1984
- Kathleen Wilhoite
- Â Kathy 1 episode, 1984
- Kate Vernon
- Â Christy 1 episode, 1984
- Christopher Rydell
- Â Craig Duvall 1 episode, 1984
- Edith Fields
- Â Mrs. Sharon Fletcher 1 episode, 1984
- Sam Kwasman
- Â Dennis McKay 1 episode, 1984
- Warren Munson
- Â Fred Lambert 1 episode, 1984
- Bill Gratton
- Â Janitor 1 episode, 1984
- Jesse Welles
- Â Ms. Deborah Henley 3 episodes, 1985-1989
- Peter Van Norden
- Â Janitor 1 episode, 1985
- William Cort
- Â Dr. Hubert Witt 1 episode, 1985
- Michael Alldredge
- Â Young Jake Keaton 1 episode, 1985
- Kim Sebastian
- Â Eunice 1 episode, 1985
- Fran Robinson
- Â Judy 1 episode, 1985
- Simon Burgess
- Â Student 1 episode, 1985
- Corey Feldman
- Â Walter - Dewey Award Student Finalist 1 episode, 1986
- Peter Scolari
- Â Paul Kenter 1 episode, 1986
- Jerry Hardin
- Â Mr. Bidney 1 episode, 1986
- Christine Belford
- Â Victoria Hurstenberg 1 episode, 1986
- Ashley Bank
- Â Rhonda 2 episodes, 1986-1987
- Anthony Tyler Quinn
- Â Clete 1 episode, 1986
- Marietta DePrima
- Â Simone 1 episode, 1986
- Laura Jacoby
- Â Jill 2 episodes, 1986-1987
- Christopher Bradley
- Â Dave Rubin 1 episode, 1986
- Gracie Harrison
- Â Mrs. Hillman 2 episodes, 1986-1987
- Janice Lynde
- Â Monica 1 episode, 1986
- Larry Cox
- Â Mike 3 episodes, 1986-1989
- George Pentecost
- Â Eric Nordstrom 1 episode, 1986
- Jane Downs
- Â Photographer 1 episode, 1986
- Barbara Barrie
- Â Aunt Rosemary 1 episode, 1987
- Stuart Pankin
- Â Marv 1 episode, 1987
- Rain Phoenix
- Â Ashley Berkhart 1 episode, 1987
- Tracy Camilla Johns
- Â Dana 1 episode, 1987
- Lucy Butler
- Â Christine 1 episode, 1987
- Lilly Moon
- Â Nancy 1 episode, 1987
- Stephen Dorff
- Â Martin 1 episode, 1988
- Mike Hagerty
- Â Vinnie 1 episode, 1988
- Hilary Shepard
- Â Yvette 1 episode, 1988
- Susan Kohler
- Â Mrs. Richards 1 episode, 1988
- Jena Vallee
- Â Erica 1 episode, 1988
- Marianne Muellerleile
- Â Cecelia 1 episode, 1989
- Karyn O'Bryan
- Â Pippi 1 episode, 1989
- Marie Denn
- Â Eva Martin 1 episode, 1989
- Ron Jarvis
- Â Clown 1 episode, 1989
- Nancy Lenehan
- Â Roberta 1 episode, 1982
- Bridgette Andersen
- Â Young Mallory 1 episode, 1982
- William G. Schilling
- Â Customer #2 1 episode, 1982
- Grant Heslov
- Â Doug 1 episode, 1983
- Eda Reiss Merin
- Â Woman at Airport 1 episode, 1983
- Donald Reiker
- Â Phillip 1 episode, 1983
- Jeff Shelby
- Â Co-Head Judge 1 episode, 1983
- Beverly Archer
- Â Sue Barker 1 episode, 1984
- Toni Gerry
- Â Doug's Mother 1 episode, 1984
- Kate Charleson
- Â Sandy 1 episode, 1984
- Debbie Gilbert
- Â Buffy 1 episode, 1984
- Rick Gibbs
- Â Don Caruthers 1 episode, 1984
- Irving
- Â Corky 1 episode, 1984
- Dan Ponce
- Â Shoeshine Boy 1 episode, 1985
- Maryedith Burrell
- Â Young May 1 episode, 1985
- Bronwyn Thomas
- Â Roberta 1 episode, 1985
- Chez Lister
- Â Bill 1 episode, 1985
- Melanie Jones
- Â Dr. Alexander 2 episodes, 1985-1987
- Andre Marcellous
- Â Teacher 1 episode, 1985
- Chip Hammack
- Â Ronald 1 episode, 1985
- George Newbern
- Â Eric 1 episode, 1986
- Alexandra Powers
- Â Erin 3 episodes, 1986-1989
- Mason Adams
- Â Professor Lloyd Rhodes 1 episode, 1986
- George Coe
- Â Justin Phillips 1 episode, 1986
- Elsa Raven
- Â Mildred Atkins 1 episode, 1986
- Jenny Havens
- Â Shelley 2 episodes, 1986-1987
- Meg Wyllie
- Â Mrs. Leahy 1 episode, 1987
- Kim Gillingham
- Â Karen 1 episode, 1987
- Dana Andersen
- Â Monica 1 episode, 1987
- Dana Stevens
- Â Val 1 episode, 1987
- Tim Haldeman
- Â Roger 1 episode, 1987
- Brad Kesten
- Â Brad Hallinan 1 episode, 1987
- Elle Nucci
- Â Brooke 1 episode, 1987
- Malachi Pearson
- Â Eugene 1 episode, 1988
- Rosanna Huffman
- Â Alice 1 episode, 1988
- Gwen Banta
- Â Beth 1 episode, 1988
- Sandra Canning
- Â Alison 1 episode, 1988
- Maura Tierney
- Â Darlene 1 episode, 1989
- Stephen Lee
- Â Mr. Parker 1 episode, 1989
- Scott LaRose
- Â Lobster 1 episode, 1989
- Joshua Shelley
- Â Sam 1 episode, 1989
- Nina Mann
- Â Mrs. Williams 1 episode, 1989
- Ann Nelson
- Â Mrs. Crenshaw 1 episode, 1982
- Charles Douglass
- Â Alternate Head Judge 1 episode, 1983
- William Boyett
- Â Policeman 1 episode, 1984
- Ernest Harada
- Â Pastor 1 episode, 1984
- Marcianne Warman
- Â Ellen Barker 1 episode, 1984
- Shirley Prestia
- Â Receptionist 1 episode, 1985
- Mark Marias
- Â Young Robert Keaton 1 episode, 1985
- Willie Garson
- Â Walter 1 episode, 1986
- Joan McMurtrey
- Â Mrs. Kaufman 2 episodes, 1986-1987
- Cynthia Carle
- Â Betty Boswell 1 episode, 1986
- Kerry Remsen
- Â Reenie Crawford 1 episode, 1986
- James MacNerland
- Â Pete 1 episode, 1986
- Sarah Jo Martin
- Â Roger's Girlfriend 1 episode, 1987
- Milton James
- Â Waiter 1 episode, 1987
- Maria Bradley
- Â Constance 1 episode, 1987
- Steve Heineman
- Â Ron 1 episode, 1987
- Hank Azaria
- Â Joe 1 episode, 1988
- Michelle Collins
- Â Louise 1 episode, 1988
- Matt Levin
- Â Billy 1 episode, 1988
- Daniel Baldwin
- Â Holworthy 1 episode, 1989
- John Lavachielli
- Â Waiter 1 episode, 1989
- Daniel Weisman
- Â Marc 1 episode, 1989
- Paul McIsaac
- Â Judge Cameron 1 episode, 1989
- Audrey S. Freudberg
- Â Student 1 episode, 1989
- Carlos Lacamara
- Â Petey 1 episode, 1983
- Lily Mariye
- Â Eleanor 1 episode, 1984
- Hanna Landy
- Â Mrs. Kretzer 1 episode, 1985
- Todd Jeffries
- Â Eddie 1 episode, 1986
- Nan Vernon
- Â Margie Hanley 1 episode, 1986
- Jonna Lee
- Â Tammy Okun 1 episode, 1987
- Ira Heiden
- Â Sam 1 episode, 1987
- Margaret Nagle
- Â Jill 1 episode, 1987
- Robert Klein
- Â Roger 'Eggy' Erdman 1 episode, 1988
- Jennifer Flackett
- Â Connie 1 episode, 1988
- Benji Schulman
- Â Eric 1 episode, 1988
- Robert Torti
- Â Jack McDowell 1 episode, 1989
- Jane Daly
- Â Christine Chadway 1 episode, 1989
- John J. York
- Â Matthews 1 episode, 1989
- Dan Gilvezan
- Â Officer Steele 1 episode, 1989
- Sarah McCrary
- Â Violet 1 episode, 1989
- Michael B. Moynahan
- Â Grover Garver 3 episodes, 1983-1986
- Richard Stahl
- Â Stu Devin 1 episode, 1985
- Wiley Harker
- Â Mr. Kretzer 1 episode, 1985
- Reid Shelton
- Â Charles Okun Jr. 1 episode, 1987
- Bever-Leigh Banfield
- Â Nurse 1 episode, 1988
- Alex Zuckerman
- Â Davey 1 episode, 1989
- Minnie Summers Lindsey
- Â Rosemary 1 episode, 1989
- Charles Bouvier
- Â Officer Larson 1 episode, 1989
- Mark Barnet
- Â Strauss 1 episode, 1989
- Christopher Joyce
- Â Young Man #2 2 episodes, 1984-1987
- Rob Steinberg
- Â Neighbor 1 episode, 1985
- Joseph Della Sorte
- Â Mr. Parsons 1 episode, 1988
- Jo Jean Pagano
- Â Nurse 1 episode, 1988
- Marissa Rosen
- Â Child #1 1 episode, 1989
- Mimi Cozzens
- Â Mrs. Clark 1 episode, 1989
- Stan Roth
- Â Doctor 1 episode, 1985
- Barbara Minkus
- Â Neighbor 1 episode, 1985
- Adrian Sparks
- Â Man at School Board Meeting 1 episode, 1988
- Darrell Thomas Utley
- Â Josh Richards 1 episode, 1988
- John I. Moseley
- Â Surgical Assistant 1 episode, 1988
- Maris Clement
- Â Ginny 1 episode, 1989
- Ginny Wohland
- Â Child #2 1 episode, 1989
- Linda Klein
- Â Anesthesiologist 1 episode, 1988
- Nichole Francois
- Â Child #3 1 episode, 1989
- Mark Moses
- Â Rick Albert 1 episode, 1986
- Macon McCalman
- Â Professor Spanos 1 episode, 1986
- Ellen Latzen
- Â Michelle Davis 1 episode, 1987
- Penelope Ann Miller
- Â Joyce 1 episode, 1987
- Wil Wheaton
- Â Timothy Higgins 1 episode, 1987
- Suzie Plakson
- Â Doris 1 episode, 1987
- Lee Garlington
- Â Beth Davis 1 episode, 1987
- Alisan Porter
- Â Child 1 episode, 1987
- Jay Thomas
- Â Jerry DiNello 1 episode, 1987
- Ken Lerner
- Â Mr. Feinman 1 episode, 1987
- Victor DiMattia
- Â Eddie 1 episode, 1987
- Annie O'Donnell
- Â Blue Mama 1 episode, 1987
- Josh Clark
- Â Ray Davis 1 episode, 1987
- Pete Schrum
- Â Nick 1 episode, 1987
- Sandy Ward
- Â Carl Norback 1 episode, 1987
- Jonathan Emerson
- Â Colin Spencer 1 episode, 1987
- Max Segar
- Â Mr. Carlisle 1 episode, 1987
- Katherine James
- Â Connie 1 episode, 1987
- Chad McCann
- Â Delivery Boy 1 episode, 1987
- Stephen Baldwin
- Â Bobby 1 episode, 1988
- Liz Sheridan
- Â Ginny McCoy 1 episode, 1988
- Trevor Eyster
- Â Young Alex 1 episode, 1988
- Nicholas Rutherford
- Â Young Skippy 1 episode, 1988
- Helen Page Camp
- Â Vera 1 episode, 1988
- Diana Bellamy
- Â Dr. Eileen Davidson 1 episode, 1988
- Don Amendolia
- Â Tom 1 episode, 1988
- Kathleen Dennehy
- Â Janie 1 episode, 1988
- Ray Reinhardt
- Â Bill 1 episode, 1988
- Richard Brestoff
- Â Professor Webster 1 episode, 1988
- Brownie McGhee
- Â Eddie Dupre 1 episode, 1988
- Shannon Macpherson
- Â Young Mallory 1 episode, 1988
- Lyman Ward
- Â John Willis 1 episode, 1989
- Gary Grubbs
- Â Mr. Willis 1 episode, 1989
- Vic Polizos
- Â Dave McPhee 1 episode, 1989
- Florence Sundstrom
- Â Woman 1 episode, 1989
- Wendy Wells-Gunkel
- Â Party Girl / ... (uncredited) 4 episodes, 1987
- Bill Baker
- Â Party Guest / ... (uncredited) 3 episodes, 1982-1986
- Lori Randolph
- Â Blonde Little Girl / ... (uncredited) 2 episodes, 1983-1986
- Garrett Merriman
- Â Baby Andrew 'Andy' Keaton (uncredited) 2 episodes, 1985
- Tyler Merriman
- Â Baby Andrew 'Andy' Keaton (uncredited) 2 episodes, 1985
- Gunnar Magg
- Â Father #1 (uncredited) 1 episode, 1983
- Ford Austin
- Â Todd (uncredited) 1 episode, 1984
- Marc Wasserman
- Â Ted (uncredited) 1 episode, 1984
- Richard Vidan
- Â Jail Guard (uncredited) 1 episode, 1984
- Heather Warren
- Â Lady in Audience (uncredited) 1 episode, 1984
- Tracey Birdsall
- Â Cammie (uncredited) 1 episode, 1986
- Tom Willett
- Â Telephone Panelist (uncredited) 1 episode, 1986
- Laura Esterman
- Â Waitress (uncredited) 1 episode, 1987
- Kelly Gallant
- Â Carnival Goer (uncredited) 1 episode, 1987
- Mike Starr
- Â Wally Carello (uncredited) 1 episode, 1988
- Tyler Bowe
- Â Man (uncredited) 1 episode, 1988
- Gary Costello
- Â 1986-1987 (uncredited) 1 episode, 1988
- David Bowe
- Â Neil Cooper (uncredited) 1 episode, 1989
- Danny Nero
- Â Train Passenger (uncredited) 1 episode, 1989
