- Eddie Murphy
- Self
- Tatyana Ali
- Singing Child (sketch)
- Billie Allen
- Eddie's Aunt (sketch)
- Clebert Ford
- Uncle Lester (sketch)
- Geri Gibson
- Card Player #2 (sketch)
- Birdie M. Hale
- Aunt Rose (sketch)
- Tiger Haynes
- Card Player #3 (sketch)
- Leonard Jackson
- Uncle Gus (sketch)
- Samuel L. Jackson
- Eddie's Uncle (sketch)
- Jody Jones
- Eddie's Cousin (sketch)
- Davenia McFadden
- Eddie's Aunt (sketch)
- Gwen McGee
- Eddie's Mother (sketch)
- Lex Monson
- Card Player #4 (sketch)
- Warren Morris
- Poetry Reader (sketch)
- Deon Richmond
- Little Eddie (sketch)
- Basil Wallace
- Eddie's Father (sketch)
- Damien Dante Wayans
- Child Running in House (sketch)
- Ellis Williams
- Eddie's Uncle (sketch)
- Carol Woods
- Eddie's Aunt (sketch)
- James Brown III
- Thanksgiving Guest (sketch)
- Michelle Davison
- Thanksgiving Guest (sketch)
- J.D. Hall
- Party Guest (sketch)
- Barbara Harris
- Thanksgiving Guest (sketch)
- John Lafayette
- Thanksgiving Guest (sketch)
- Eyde Byrde
- Mrs. Butts (sketch)
- Kim Wayans
- Interviewed Fan
