- Katharine Hepburn
- Jade Tan
- Walter Huston
- Ling Tan
- Aline MacMahon
- Ling Tan's Wife
- Akim Tamiroff
- Wu Lien
- Turhan Bey
- Lao Er Tan - Middle Son
- Hurd Hatfield
- Lao San Tan - Youngest Son
- J. Carrol Naish
- Japanese Kitchen Overseer
- Agnes Moorehead
- Third Cousin's Wife
- Henry Travers
- Third Cousin
- Robert Bice
- Lao Ta Tan - Eldest Son
- Robert Lewis
- Capt. Sato
- Frances Rafferty
- Orchid Tan - Lao Ta's Wife
- Jacqueline deWit
- Wu Lien's Wife
- Clarence Lung
- Fourth Cousin
- Paul E. Burns
- Shen - Neighbor
- Anna Demetrio
- Wu Sao
- Philip Ahn
- Leader of City People
- Albert Baldo
- Japanese Soldier
- Lionel Barrymore
- Narrator
- Abner Biberman
- Capt. Yasuda
- John Bleifer
- Japanese Guard
- Luke Chan
- City Man
- Spencer Chan
- Farmer
- Marlowe Chuck
- Wu Lien's First Child
- Noel Cravat
- Japanese Guard
- Johnny Dong
- Student
- Claire Du Brey
- Hysterical Woman
- Arthur Dulac
- Japanese Soldier
- Edward Emerson
- Japanese Soldier
- Frank Eng
- Student
- Benson Fong
- Sudent
- Harold Fong
- Clerk
- Lee Tong Foo
- Innkeeper
- Wing Foo
- Student
- Paul Fung
- Farmer
- Roland Got
- Speaker with Movies
- Alex Havier
- Japanese Soldier
- Ted Hecht
- Maj. Yohagi
- Al Hill
- Japanese Officer
- David Hui
- Jade's Child
- Percy Incion
- Japanese Guard
- Pete G. Katchenaro
- Japanese Officer
- Joseph Kim
- Japanese Officer
- Paul King
- Farmer
- Eddie Lee
- City Man
- Norman Lee
- Wu Lien's Second Child
- Robert Lee
- Young Farmer
- James B. Leong
- City Man
- Jung Lim
- Farmer
- Emil Luna
- Japanese Official
- Charles Lung
- Japanese Diplomat
- Ma
- Water Buffalo
- Abraham Mirkin
- (uncredited)
- Leonard Mudie
- Old Peddler Selling Poison
- Jay Novello
- Japanese Soldier
- Frank Puglia
- Wu Lien's Old Clerk
- Jack Santos
- Japanese Guard
- Teru Shimada
- Villager
- Hayward Soo Hoo
- Orchid's First Child
- Leonard Strong
- Japanese Official
- Frank Tang
- Farmer
- Edna Mae Tom
- Chinese Woman
- Wei Fan Tseui
- Student
- Irene Tso
- Wu Lien's Third Child
- Philip Van Zandt
- Japanese Guard
- Prince Waln
- Japanese Soldier
- Richard Wang
- Japanese Soldier
- Beal Wong
- Farmer / Japanese Officer (uncredited)
- Tai Ling Wong
- Orchid's Second Child
- Victor Wong
- Japanese Officer
- Winifred Woo
- Jade's Child
- Richard Yee
- Student
- Beverly Young
- Orchid's Second Child
