- Quinton Flynn
- Â Marcus Damon 48 episodes, 2006-2008
- Colleen O'Shaughnessey
- Â Yoshino 'Yoshi' Fujieda / ... 48 episodes, 2006-2008
- Brian Beacock
- Â Agumon / ... 47 episodes, 2006-2008
- Crispin Freeman
- Â Thomas H. Norstein 47 episodes, 2006-2008
- Dorothy Elias-Fahn
- Â Lalamon / ... 47 episodes, 2006-2008
- Skip Stellrecht
- Â Gaomon / ... 44 episodes, 2006-2008
- Steve Blum
- Â Falcomon / ... 36 episodes, 2006-2008
- Brianne Brozey
- Â Keenan Crier 34 episodes, 2006-2008
- Kate Higgins
- Â Miki Kurosaki / ... 34 episodes, 2006-2008
- Stephanie Sheh
- Â Megumi Shirakawa / ... 31 episodes, 2006-2008
- Melissa Fahn
- Â Kristy Damon 28 episodes, 2006-2008
- Jeff Nimoy
- Â Kamemon / ... 27 episodes, 2006-2008
- Jamieson Price
- Â Commander Richard Sampson / ... 26 episodes, 2006-2008
- Kirk Thornton
- Â Homer Yushima / ... 25 episodes, 2006-2008
- Sam Riegel
- Â Kudamon / ... 23 episodes, 2006-2008
- Mary Elizabeth McGlynn
- Â Sarah Damon / ... 25 episodes, 2006-2008
- Michael Lindsay
- Â Gotsumon / ... 21 episodes, 2007-2008
- Brian Palermo
- Â Akihiro Kurata 21 episodes, 2006-2008
- Mona Marshall
- Â Frigimon / ... 15 episodes, 2008
- Wally Wingert
- Â BanchoLeomon / ... 14 episodes, 2006-2008
- Richard Epcar
- Â Merukimon / ... 14 episodes, 2007-2008
- Paul St. Peter
- Â SaberLeomon / ... 10 episodes, 2006-2008
- Doug Stone
- Â Director Hashima 8 episodes, 2007-2008
- Henry Dittman
- Â Craniamon / ... 8 episodes, 2008
- Kari Wahlgren
- Â Relena Norstein 8 episodes, 2006-2008
- Dave Wittenberg
- Â Kouki Tsubasa / ... 8 episodes, 2008
- Michelle Ruff
- Â Michelle Crier / ... 8 episodes, 2008
- Terrence Stone
- Â Biyomon / ... 7 episodes, 2007-2008
- Christopher Darga
- Â Ivan / ... 7 episodes, 2008
- Philece Sampler
- Â Nanami / ... 8 episodes, 2008
- Dave Mallow
- Â Otamamon / ... 7 episodes, 2007-2008
- Adam Bitterman
- Â Franz Norstein 6 episodes, 2008
- Joe Ochman
- Â Kevin Crier / ... 8 episodes, 2008
- Susan Boyajian
- Â Piximon / ... 5 episodes, 2008
- Brad Sherwood
- Â Gallantmon 5 episodes, 2008
- Michael Sorich
- Â Baromon 4 episodes, 2008
- Neil Kaplan
- Â Pumpkinmon / ... 5 episodes, 2008
- Brian Fairlee
- Â Magnamon 4 episodes, 2008
- Lex Lang
- Â Drimogemon / ... 3 episodes, 2006-2008
- Kyle Hebert
- Â Belphemon Rage Mode 4 episodes, 2008
- Debi Mae West
- Â Young Marcus Damon 4 episodes, 2008
- Chris Edgerly
- Â Dynasmon / ... 3 episodes, 2008
- R. Martin Klein
- Â Gomamon / ... 4 episodes, 2008
- Peter Spellos
- Â Omnimon / ... 3 episodes, 2007-2008
- Dan Woren
- Â DemiMeramon / ... 2 episodes, 2007
- Tom Fahn
- Â DemiDevimon #3 / ... 2 episodes, 2007
- Melodee Spevack
- Â Blossomon / ... 2 episodes, 2008
- Michael McConnohie
- Â Cherrymon / ... 2 episodes, 2008
- Jonathan David Cook
- Â King Drasil 7D6 2 episodes, 2008
- Michael P. Greco
- Â Komiya 1 episode, 2007
- Jonathan Fahn
- Â Connor Shitori / ... 1 episode, 2007
- Susan Silo
- Â Grandma Norstein 1 episode, 2008
- Yuri Lowenthal
- Â Hitoshi 'Neon' Hanamura / ... 1 episode, 2006
- Beau Billingslea
- Â Leopardmon 1 episode, 2008
- Travis Willingham
- Â Boomer / ... 1 episode, 2007
- Dave Bushnell
- Â LoadKnightmon 1 episode, 2008
- Steve Kramer
- Â Vilemon 1 episode, 2007
- Mari Devon
- Â King Drasil Core 1 episode, 2008
- Michael Pink
- Â Doctor 1 episode, 2008
