- Simon Helberg
- Â Simon 14 episodes, 2007
- Derek Waters
- Â Derek 14 episodes, 2007
- Jake Johnson
- Â Jake 6 episodes, 2007
- Eric Edelstein
- Â Eric 6 episodes, 2007
- Eric Filipkowski
- Â Eric 6 episodes, 2007
- Bob Odenkirk
- Â Vance Hammersly / ... 3 episodes, 2007
- Paula Christensen
- Â Julie 3 episodes, 2007
- Richard Dunn
- Â Sir / ... 3 episodes, 2007
- Busy Philipps
- Â Julia 2 episodes, 2007
- Brendan Hunt
- Â Karaoke DJ 2 episodes, 2007
- Marianna Palka
- Â Sophie 2 episodes, 2007
- Samm Levine
- Â Sam 2 episodes, 2007
- Joe Nunez
- Â Karaoke Dent 2 episodes, 2007
- Emily Maya Mills
- Â Christie 2 episodes, 2007
- Kellie Matteson
- Â Kelly / ... 2 episodes, 2007
- Julie Mitchell
- Â The Deaf Girl 2 episodes, 2007
- Sue Foley
- Â Karaoke Dent 2 episodes, 2007
- Apul Patel
- Â Phil 2 episodes, 2007
- Michael Cera
- Â The Bouncer 1 episode, 2007
- June Diane Raphael
- Â June 1 episode, 2007
- Casey Wilson
- Â Anna 1 episode, 2007
- Stephanie Courtney
- Â Glenda the Birthday Girl 1 episode, 2007
- Jocelyn Towne
- Â Claire 1 episode, 2007
- Steve Agee
- Â Ticketless Giant 1 episode, 2007
- Bobby Mort
- Â Art Gallery Patron 1 episode, 2007
- Camille Chen
- Â Camille 1 episode, 2007
- Laurel Coppock
- Â Art Gallery Patron 1 episode, 2007
- Brooke Bloom
- Â Jenny 1 episode, 2007
- Emily Rutherfurd
- Â Sandy 1 episode, 2007
- Andrew Friedman
- Â Father O'Leary 1 episode, 2007
- Jill Bartlett
- Â Jill 1 episode, 2007
- Lara Everly
- Â Simon's Girlfriend 1 episode, 2007
- Drew Droege
- Â Surprise Guest 1 episode, 2007
- Perry F. Caravello
- Â Sherlock Helms 1 episode, 2007
- Craig Anstett
- Â Stage Manager 1 episode, 2007
- Tracy Thorpe
- Â Katty Mulray 1 episode, 2007
- Jason Pardo
- Â Officer Muldoon 1 episode, 2007
- Jeannie Cole
- Â The Pee Girl 1 episode, 2007
- Chris Kattan
- Â Self (uncredited) 1 episode, 2007
