- Judd Hirsch
- Â John Lacey 90 episodes, 1988-1992
- Jere Burns
- Â Kirk Morris 90 episodes, 1988-1992
- Jane Carr
- Â Louise Mercer 90 episodes, 1988-1992
- Isabella Hofmann
- Â Kate McCarron 90 episodes, 1988-1992
- Tom Willett
- Â Tom 75 episodes, 1988-1992
- Billie Bird
- Â Mrs. Margie Philbert 82 episodes, 1988-1992
- Harry Groener
- Â Ralph Drang 68 episodes, 1988-1991
- Susan Walters
- Â Mary Beth Sutton 56 episodes, 1990-1992
- William O'Leary
- Â Ben Conners 22 episodes, 1991-1992
- Marietta DePrima
- Â Annie 15 episodes, 1991-1992
- Olivia Brown
- Â Denise 13 episodes, 1990-1991
- Peter Jurasik
- Â Brad 8 episodes, 1989-1990
- Ruben Santiago-Hudson
- Â Curtis / ... 6 episodes, 1990-1992
- Richard Blum
- Â The Bartender / ... 6 episodes, 1989-1992
- Carlene Watkins
- Â Wendy 5 episodes, 1988-1989
- Ben Savage
- Â Matthew Lacey 5 episodes, 1988-1990
- Cu Ba Nguyen
- Â Chow Ling 5 episodes, 1989-1990
- Patrick Puccinelli
- Â Officer Biggs / ... 5 episodes, 1989-1991
- Tim Jones
- Â Calvin / ... 5 episodes, 1990-1992
- Deborah Harmon
- Â Wendy Lacey 5 episodes, 1990-1991
- Greg Salata
- Â Mitch 4 episodes, 1991
- Raye Birk
- Â Dr. Hendricks 4 episodes, 1990-1992
- Billy Corben
- Â Matthew Lacey / ... 3 episodes, 1990-1991
- Christine Cattell
- Â Jennifer / ... 3 episodes, 1990-1992
- Pat Reilly
- Â Stretch Hendricks / ... 3 episodes, 1990
- Mindy Seeger
- Â Jackie 3 episodes, 1991
- Ele Keats
- Â Sandy / ... 3 episodes, 1990
- DeLane Matthews
- Â Dr. Janet Benjamin 3 episodes, 1991
- Peter Iacangelo
- Â Mort 3 episodes, 1991
- William Sadler
- Â Ken 2 episodes, 1988-1989
- Sam McMurray
- Â Mike 2 episodes, 1988-1989
- Nina Foch
- Â Mrs. Lacey 2 episodes, 1990-1991
- Dakin Matthews
- Â David / ... 2 episodes, 1988-1989
- Robin Strasser
- Â Brooke Collins 2 episodes, 1990
- Lorenzo Lamas
- Â Alejandro Braceros 2 episodes, 1991
- Robin Greer
- Â Robin / ... 2 episodes, 1990-1991
- George Hearn
- Â Frank Hollander 2 episodes, 1991
- Trevor Eve
- Â Ricky Fortune 2 episodes, 1989
- Michele Pawk
- Â Barbara Denison 2 episodes, 1990
- Megan Mullally
- Â Molly 2 episodes, 1991
- Jack Manning
- Â Funeral Director / ... 2 episodes, 1990-1991
- Joanne McGee
- Â Andrea 2 episodes, 1991
- Cliff Norton
- Â Pilot 2 episodes, 1990
- Eda Reiss Merin
- Â Mrs. Spencer / ... 2 episodes, 1989-1991
- John Ingle
- Â Judge Bradford / ... 2 episodes, 1990-1992
- Ellen Hilton
- Â Flower Girl / ... 2 episodes, 1990-1992
- John Carter
- Â Judge Humphrey 2 episodes, 1991
- Marlene Mancini
- Â Florence Kellem / ... 2 episodes, 1991
- Deasa Turner
- Â Linda / ... 2 episodes, 1991
- Adam Carl
- Â Mladen 2 episodes, 1990
- John David Conti
- Â Leo 2 episodes, 1991-1992
- Grace Albertson
- Â Mourner #1 / ... 2 episodes, 1990-1991
- Laurie Shiers
- Â Female Student 2 episodes, 1990
- Lisa Long
- Â Mourner #2 / ... 2 episodes, 1991
- Gino De Mauro
- Â Bobby Meyer 2 episodes, 1990
- Larry Spinak
- Â Male Student #1 2 episodes, 1990
- Keith Burns
- Â Clerk / ... 2 episodes, 1990
- Patrick Day
- Â Male Student #2 2 episodes, 1990
- Tim Jones
- Â Calvin 2 episodes, 1992
- Tim Haldeman
- Â Husband / ... 2 episodes, 1990-1991
- Gracie Harrison
- Â Erin 2 episodes, 1989-1991
- Heather Elizabeth Parkhurst
- Â Cindy / ... 2 episodes, 1991-1992
- Peter Smith
- Â John at 17 & 22 / ... 2 episodes, 1990-1991
- David Pressman
- Â Larry / ... 2 episodes, 1991-1992
- Nicky Katt
- Â Amorous Male Student 2 episodes, 1989-1990
- Carlos R. Bermúdez
- Â Busboy 2 episodes, 1992
- Richard Portnow
- Â Harry 1 episode, 1988
- Lonny Price
- Â Andrew Garberg 1 episode, 1988
- Jennifer Bassey
- Â Eleanor Guthrie 1 episode, 1988
- Woody Harrelson
- Â Richard 1 episode, 1989
- Wendy Schaal
- Â Lisa 1 episode, 1989
- Annie Golden
- Â Sylvia 1 episode, 1989
- Gerrit Graham
- Â Gary 1 episode, 1989
- Cleavon Little
- Â Tony Larkin 1 episode, 1989
- Gwen Verdon
- Â Yvonne 1 episode, 1989
- Elizabeth Maclellan
- Â Barbara 1 episode, 1989
- Joanne Gibson
- Â Gloria 1 episode, 1989
- Jennifer Runyon
- Â Karen 1 episode, 1988
- Cristine Rose
- Â Gloria 1 episode, 1988
- Donald Craig
- Â Father of the Bride 1 episode, 1988
- Bob Snead
- Â Steven Guthrie 1 episode, 1988
- Jeffrey DeMunn
- Â Neil Cramer 1 episode, 1989
- Jan Hooks
- Â Suzanne 1 episode, 1989
- Barbara Rhoades
- Â Marie 1 episode, 1989
- Clive Revill
- Â Louise's Dad 1 episode, 1989
- Keone Young
- Â Mr. Yoshimura 1 episode, 1989
- Elizabeth Franz
- Â Emma 1 episode, 1989
- Stephen Elliott
- Â Phil Lacey 1 episode, 1989
- Pat Crawford Brown
- Â Kirk's Mom 1 episode, 1989
- Oliver Clark
- Â Arthur Prescott 1 episode, 1989
- Elizabeth Savage
- Â Wanda 1 episode, 1989
- Nancy Lane
- Â Carol 1 episode, 1989
- Freddie Garrity
- Â Freddie Garrity 1 episode, 1989
- Jeanette Nolan
- Â Clara 1 episode, 1990
- Jane Daly
- Â Gail 1 episode, 1990
- Shiri Appleby
- Â Girl 1 episode, 1988
- Lee Arenberg
- Â Caroler #1 1 episode, 1988
- Catherine MacNeal
- Â The Party Guest 1 episode, 1988
- Jenny Agutter
- Â Sarah 1 episode, 1989
- Shannon Tweed
- Â Margo 1 episode, 1989
- Jeff Garlin
- Â Deliveryman 1 episode, 1989
- Rod McCary
- Â T. Pat Conner 1 episode, 1989
- Mary Carver
- Â Mom 1 episode, 1989
- Tiiu Leek
- Â The Anchorwoman 1 episode, 1989
- Janice Lynde
- Â Dr. Davenport 1 episode, 1989
- William Glover
- Â Father Gorman 1 episode, 1989
- Yuri Ogawa
- Â Mrs. Yoshimura 1 episode, 1989
- Doug Carfrae
- Â The Waiter 1 episode, 1989
- Mary Anne Schafer
- Â Helen 1 episode, 1989
- Corbin Bernsen
- Â Blake McCarron 1 episode, 1990
- Kevin Dunn
- Â Bob Morris 1 episode, 1990
- Mike Hagerty
- Â Al 1 episode, 1990
- Nancy Lenehan
- Â Mrs. Williams 1 episode, 1990
- Doug Sheehan
- Â Jason Fowler 1 episode, 1990
- Gordon Clapp
- Â Dave Travis 1 episode, 1990
- Sab Shimono
- Â Charlie Moura 1 episode, 1990
- Murphy Cross
- Â Female Piano Player 1 episode, 1990
- George Petrie
- Â Lester 1 episode, 1990
- Juliet Sorci
- Â Melissa 1 episode, 1990
- Patrick Collins
- Â Lionel 1 episode, 1990
- Gina Belafonte
- Â Sudha 1 episode, 1990
- Patty Toy
- Â Young Mother 1 episode, 1990
- Judd Trichter
- Â Danny 1 episode, 1990
- Sanford Jensen
- Â Barry 1 episode, 1990
- Timothy Jones
- Â Waiter 1 episode, 1990
- Wayne Tippit
- Â Everett Sutton 1 episode, 1991
- Harold Gould
- Â William Shakespeare 1 episode, 1992
- Ned Eisenberg
- Â C.J. 1 episode, 1992
- Elayne Boosler
- Â Joanne 1 episode, 1992
- Betsy Randle
- Â Fay 1 episode, 1988
- Robert G. Lee
- Â The Waiter 1 episode, 1988
- Christopher Blande
- Â Caroler #2 1 episode, 1988
- Morgan Brittany
- Â Liz 1 episode, 1989
- Mary Pat Gleason
- Â Secretary 1 episode, 1989
- Lila Kaye
- Â Audrey 1 episode, 1989
- Angela Paton
- Â Mother Superior 1 episode, 1989
- Patricia Ayame Thomson
- Â Sashiko 1 episode, 1989
- John Lavachielli
- Â Orlando 1 episode, 1989
- Larry McCormick
- Â The Reporter 1 episode, 1989
- Brynn Thayer
- Â Terry 1 episode, 1990
- Lisa Aliff
- Â Ski Bunny 1 episode, 1990
- Denise Gallup
- Â Twin Girlfriend 1 episode, 1990
- Paul Barselou
- Â Lloyd 1 episode, 1990
- Valorie Armstrong
- Â Blair 1 episode, 1990
- Nathan Jung
- Â Husband 1 episode, 1990
- Meredith Baker
- Â Babysitter 1 episode, 1990
- Anita Barone
- Â Connie 1 episode, 1991
- Elizabeth Morehead
- Â Donna 1 episode, 1991
- Lane Davies
- Â Walter Harrison 1 episode, 1991
- Alice Hirson
- Â Mrs. Morris 1 episode, 1991
- Patrick Collins
- Â Charlie 1 episode, 1991
- Peter Jason
- Â Bill Conners 1 episode, 1992
- Michael E. Knight
- Â Freddie 1 episode, 1992
- Cliff Bemis
- Â Marvin 1 episode, 1992
- Sylvia Sidney
- Â Mrs. Lumenski 1 episode, 1988
- Brent Jennings
- Â Frank 1 episode, 1988
- Jennifer Hirsch
- Â Karen's Friend 1 episode, 1988
- Nancy Linari
- Â Dr. Osbourne 1 episode, 1989
- Tony Mandarich
- Â Rudy 1 episode, 1989
- Donald Gibb
- Â Frenchie 1 episode, 1990
- Leslie Bevis
- Â Jessica Stone 1 episode, 1990
- Nedra Volz
- Â Dotty 1 episode, 1990
- Dian Gallup
- Â Twin Girlfriend 1 episode, 1990
- Helen Page Camp
- Â Aunt Trudy 1 episode, 1990
- Perry Anzilotti
- Â Mr. Babyface 1 episode, 1990
- Kathryn Danielle Hirsch
- Â Stacy 1 episode, 1990
- Milton James
- Â Cab Driver 1 episode, 1990
- Gwendolyn Shepherd
- Â Smoke-Ender 1 episode, 1990
- Kenny McMurphy
- Â Clerk 1 episode, 1990
- Elsa Raven
- Â Barbara Olafson 1 episode, 1991
- Lela Ivey
- Â Betsy 1 episode, 1991
- Kevin Scannell
- Â Rocco 1 episode, 1991
- Diana Barrows
- Â Tina 1 episode, 1991
- Irina Davidoff
- Â Natasha 1 episode, 1991
- Melora Walters
- Â Maria 1 episode, 1992
- Deborah Shelton
- Â John's Fantasy Woman 1 episode, 1992
- Kristen Cloke
- Â Annette 1 episode, 1992
- Michael McManus
- Â Bruce 1 episode, 1992
- Debbie Gregory
- Â Naomi 1 episode, 1992
- Kristine Blackburn
- Â Sarah 1 episode, 1992
- Daniel Zacapa
- Â Brian 1 episode, 1988
- Ellen Ratner
- Â Molly 1 episode, 1989
- Miguel A. Núñez Jr.
- Â Henry 1 episode, 1990
- Bill Henderson
- Â Pete 1 episode, 1990
- Jennifer Flackett
- Â Smoke-Ender 1 episode, 1990
- Nita Whitaker
- Â Female Officer 1 episode, 1990
- Paige Pengra
- Â Jessica at 17 & 22 1 episode, 1990
- Bo Sharon
- Â Boy 1 episode, 1990
- Michael Gordon Bell
- Â Billy 1 episode, 1990
- Karen Ironside
- Â Mindy 1 episode, 1990
- Mihaly 'Michu' Meszaros
- Â Mishka 1 episode, 1991
- William Boyett
- Â Officer #1 1 episode, 1991
- Dan Gilvezan
- Â Pete 1 episode, 1991
- Nicholas Cascone
- Â Robber 1 episode, 1991
- Kendra Booth
- Â Terry 1 episode, 1991
- Bruce R. Fisher
- Â Delivery Man 1 episode, 1991
- Nick Tate
- Â Brian Courtney 1 episode, 1992
- John Calvin
- Â Richard 1 episode, 1992
- Scott Bryce
- Â Mary Beth's Fantasy Man 1 episode, 1992
- Jeremy Stevens
- Â Dick 1 episode, 1992
- Cherie Michan
- Â Heather 1 episode, 1992
- David Pasquesi
- Â Smoke-Ender 1 episode, 1990
- Meg Wyllie
- Â Millie Hanson 1 episode, 1990
- Lee Weaver
- Â Snookie Reams 1 episode, 1990
- Alex Zuckerman
- Â Jason 1 episode, 1990
- John O'Leary
- Â Minister 1 episode, 1990
- Megan McGinnis
- Â Girl 1 episode, 1990
- Victoria Haas
- Â Nun 1 episode, 1990
- Don Frankel
- Â Arnie 1 episode, 1990
- Clyde Kusatsu
- Â Officer #2 1 episode, 1991
- Paul Eiding
- Â Emcee 1 episode, 1991
- Jerome Courtland
- Â Frank 1 episode, 1991
- Mario Machado
- Â Male Newscaster 1 episode, 1991
- Glen Mauro
- Â Danny 1 episode, 1991
- Micah Rowe
- Â Kid #1 1 episode, 1991
- Laura Jacobson
- Â Receptionist 1 episode, 1991
- Victoria Howden
- Â Marcie 1 episode, 1991
- Diana Castle
- Â Felicia Courtney 1 episode, 1992
- Erika Flores
- Â Jessica at 12 1 episode, 1990
- Kyle Scott Jackson
- Â Desk Sergeant 1 episode, 1990
- Kay Perry
- Â Woman #1 1 episode, 1990
- Rick Reardon
- Â Stanley 1 episode, 1990
- Ruth Brodsley
- Â Debbie 1 episode, 1990
- Tony Hayes
- Â Smoke-Ender 1 episode, 1990
- Tristan Tait
- Â Kenny 1 episode, 1991
- Gary Mauro
- Â Donny 1 episode, 1991
- Howard McCrary
- Â Newtone #1 1 episode, 1991
- Robin Cahall
- Â Patient #1 1 episode, 1991
- Dale Harimoto
- Â Female Newscaster 1 episode, 1991
- Chambers Stevens
- Â Fraternity Member 1 episode, 1991
- Melissa Berger
- Â Wife 1 episode, 1991
- Floyd B. Jones
- Â Kid #2 1 episode, 1991
- Donald Grant
- Â Matt 1 episode, 1992
- Suzanne LaRusch
- Â Nurse 1 episode, 1992
- Dale Gonyea
- Â Piano Player 1 episode, 1992
- Susan Silverie
- Â Waitress 1 episode, 1992
- Lisa Melilli
- Â Woman #2 1 episode, 1990
- Melissa Young
- Â Heidi 1 episode, 1990
- Joshua Smith
- Â John at 12 1 episode, 1990
- Kate McNeil
- Â Carol 1 episode, 1991
- Arthur Reggie III
- Â Kid #3 1 episode, 1991
- Stephanie Blake
- Â Ramona 1 episode, 1991
- Henry Holden
- Â Patient #2 1 episode, 1991
- Perry Morgan
- Â Newtone #2 1 episode, 1991
- Cleto Augusto
- Â Max 1 episode, 1992
- Sharon Conley
- Â Woman #1 1 episode, 1992
- Sandra Wild
- Â Lorraine 1 episode, 1990
- Zane Lasky
- Â Sheldon 1 episode, 1990
- Ed Evanko
- Â Mr. Beasley 1 episode, 1990
- Art Cardoza
- Â Kid #4 1 episode, 1991
- Alfred McCrary
- Â Newtone #3 1 episode, 1991
- Karl David-Djerf
- Â Young Kirk 1 episode, 1992
- Jennifer Van Buskirk
- Â Mona 1 episode, 1992
- Bonnie Pemberton
- Â Reporter 1 episode, 1992
- Jeff Lester
- Â Cliff 1 episode, 1990
- Jason Strickland
- Â Jimmy 1 episode, 1990
- Lynne Thigpen
- Â Sarah Donnelly 1 episode, 1991
- Van Epperson
- Â Robber 1 episode, 1991
- John Poteat
- Â Brother #1 1 episode, 1991
- Martin Cassidy
- Â Man 1 episode, 1992
- Marisa Theodore
- Â Jenny 1 episode, 1992
- Matt Landers
- Â Father 1 episode, 1990
- Lori A. Fox
- Â Nurse 1 episode, 1990
- Phil Dow
- Â Brother #2 1 episode, 1991
- Nicholas Rutherford
- Â Joey 1 episode, 1990
- Jodie Mann
- Â Patron #1 1 episode, 1990
- Amy Alexandra Lloyd
- Â Nancy 1 episode, 1990
- Wayne Federman
- Â Paul 1 episode, 1990
- Laurel Ollstein
- Â Patron #2 1 episode, 1990
- James N. Hamilton
- Â Busboy 1 episode, 1990
- Stan Rodarte
- Â Support Group Member 1 episode, 1988
- Susan Kellermann
- Â Blomlika 1 episode, 1989
- Miriam Flynn
- Â Penny 1 episode, 1989
- Alan Blumenfeld
- Â Joe 1 episode, 1989
- Lee Wilkof
- Â Roy 1 episode, 1989
- Mark Arnott
- Â Ray 1 episode, 1989
- Kevin Michael Doyle
- Â Stan 1 episode, 1989
- Ambrae Jamae
- Â Young Woman 1 episode, 1990
- William Winckler
- Â Dinner guest (uncredited) 1 episode, 1988
- Larry Carr
- Â Party Guest (uncredited) 1 episode, 1989
- Richard Monahan
- Â Party Guest (uncredited) 1 episode, 1989
- Marsha Clark
- Â Jeopardy Contestant (uncredited) 1 episode, 1991
- Charles W. Bryant
- Â Waiter (uncredited) 1 episode, 1992
- Douglas Maida
- Â Waiter (uncredited) 1 episode, 1992
