- Lew Ayres
- Norman Winthrop
- June Knight
- Sue Fleming
- Alice White
- May
- Alan Dinehart
- Steve Borden
- Minna Gombell
- Nita Borden
- Eugene Pallette
- Willy Bronson
- Robert McWade
- The Grouch
- Henry Armetta
- The Italian
- Arthur Vinton
- Murphy
- Craig Reynolds
- First Bus Driver
- Jimmy Conlin
- Sid
- Harry C. Bradley
- First Dodd's Salesman
- Walter Brennan
- Niagara Falls Boatman
- Eddy Chandler
- Last Bus Driver
- Jane Darwell
- Mrs. O'Hara
- Jean Fenwick
- Schoolteacher
- Ara Haswell
- The Old Maid
- Edward Hearn
- Bus Passenger
- Eddie Kane
- Chicago Hotel Waiter
- Kay Lavelle
- Wife of Henpecked Man
- Herta Lynd
- The German Girl
- Lee Phelps
- Bus Driver
- Rolfe Sedan
- Second Dodd's Saleman
- C. Montague Shaw
- Mr. Collins
- Wini Shaw
- Singer on Bus
- Ann Shoemaker
- Mrs. O'Shaughnessy - Baby's Mother
- Will Stanton
- Drunk on Bus
- Harry Strang
- 2nd Detective
- Peggy Terry
- Toots
- Charles C. Wilson
- Detective
