- Holmes Osborne
- Richard Orchid
- David Leitch
- Frank Sledge
- Kelly Hu
- Kelly Hu / Undercover Cop
- Eric Roberts
- Eric Roberts / Police Chief
- Ernie Hudson
- Ernie Hudson / Commander
- Michael T. Weiss
- Drug Lord
- Mitchell Gaylord
- Brother
- Lin Shaye
- Samantha Jones
- Kyle Reese
- Young Frank #1
- Sean Michael Rabbit
- Young Frank #2
- Chris Palermo
- Russell Gold
- Michal Holub
- John Hu
- Josh Nathan
- Will Stillwell
- Daniel Bernhardt
- Jason Everstrong
- Matt McColm
- Commander
- Gerald Okamura
- Asian Master
- Chris O'Hara
- Frank's Stunt Double
- Sean Graham
- Stunt Coordinator
- Dax Shepard
- SFX Coordinator
- Carrie-Anne Moss
- Carrie-Anne Moss / Girlfriend in movie
- Nathan Lee Graham
- Glen Jefferies
- Patti Pelton
- Bloodfight 2: Script Supervisor / Acting Student #2
- Jason George
- Jason George / Crooked Cop
- Jason Baldwin Stewart
- Sam
- Sean Young
- Sean Young / Honey
- Kirk Ward
- Spencer Davidson
- J.B. Ghuman Jr.
- James 'The Writer'
- Ben Falcone
- Jerry Moss
- Mike Rose
- Acting Student #1
- Philip Tan
- Bruce Rhee
- Ralf Koch
- Excited Fan
- Bryndon Smith
- Excited Fan #2
- Kali Rocha
- Beth
- Jon Simanton
- Client at CAI
- Sam McMurray
- Jack Rumpkin
- Angelina Jolie
- Angelina Jolie
- Branden Morgan
- Dirk Brandon
- Jim Cody Williams
- Junior
- Susannah Hillard
- Patti Snyder / Frank's Assistant
- Richard Lewis
- Richard Lewis
- Lee Arenberg
- Barry Simpson
- Jon Gries
- Donald Buckheim
- Joel David Moore
- Joel David Moore / Prisoner (as Joel Moore)
- Al Leong
- Evil Doctor
- Michael McDonald
- Raymond Fischer
- Steven Roy
- Brett Radner
- Jeff Imada
- Martial Arts Choreographer
- Johnny Tri Nguyen
- Martial Arts Fighter
- David Storrs
- AA Member
- Debbie Allen
- Debbie Allen / Deity
- André Vippolis
- Mouse
- Tad Coughenour
- Agent #1
- Matthew Dickens
- Agent #2
- Demar Braxton
- Agent #3
- Terry Beeman
- Additional Dancer
- Hugo Weaving
- Hugo Weaving
- Chris Hogan
- Newscaster
- Aaron Bertram
- Partier
- Robert Alonzo
- Kumite fighter
- Dalton Brooks
- Frank Sledge at age 10
- Peter Jason
- (uncredited)
- Anne Moss
- (uncredited)
- Todd Schneider
- Referee
- Ben Stiller
- Commander
- Marcus Young
- Barroom Brawler
