- James Franciscus
- Moses Brody
- Mimsy Farmer
- Jean Beneyton
- Venantino Venantini
- Forsythe
- Fiamma Maglione
- Nicole Brody
- Edmund Purdom
- Danker
- Francisco Charles
- George
- Francesco Carnelutti
- Co-Pilot
- Ottaviano Dell'Acqua
- John
- Aldo Barberito
- Priest
- Roberto Santi
- Navigator
- Maria D'Incoronato
- Passenger
- Renzo Marignano
- Martinez
- Renato Cortesi
- Journalist
- Maria D'Alessandro
- Hostess
- Alessandra Stordy
- Flight Attendant
- Enrico Papa
- Charlie
- Walter Toschi
- Pilot
- Monica Scattini
- Woman in Moses' Office
- Renata Zamengo
- Mother
- Mario Maranzana
- Heart Attack Victim
- Van Johnson
- Captain Scott
- Joseph Cotten
- Milland
- Erminio Bianchi Fasani
- Passenger
- Peter Boom
- Journalist
- Dakar
- Fisherman
- Ruggero Deodato
- Man in Nicole's Restaurant
- John P. Dulaney
- Man on Boat
- Patrick Farrelly
- Mr. Dole
- Lina Franchi
- Passenger
- Michael Gaunt
- London Air Traffic Controller
- Alfonso Giganti
- Passenger
- Robert Kerman
- Chief Operator Kelman
- Alba Maiolini
- Passenger
- Giuseppe Marrocco
- Passenger
- Giovanni Morosi
- Passenger
- Nello Palladino
- Passenger
- Robert Spafford
- Milland's Senior Advisor
- John Stacy
- American Consul
- Liana Tabacchino
- Concorde Passenger
- Jake Teague
- London Air Traffic Controller
- Goffredo Unger
- Forsythe Henchman
