- Keith David
- The Depression Demon
- Zolee Griggs
- Daisy Kiongozi / Buttafly Girl (voice)
- Angelica Ross
- Dr.Niobe / Oblivion (voice)
- Gary LeRoi Gray
- W.Z.R.D.
- Coty Galloway
- Police Chief
- Nandi Nfr Ka
- Arizona Phillips
- Z Cher-Aimé
- Xerxes Hughes / Captain Zero (voice)
- Marion Toro
- Vivica Tate
- Jazz Walker
- Newscaster
- Blue Telusma
- Violet Hughes
