- Jean Harlow
- Lola Burns
- Lee Tracy
- E.J. 'Space' Hanlon
- Frank Morgan
- Pops Burns
- Franchot Tone
- Gifford Middleton
- Pat O'Brien
- Jim Brogan
- Una Merkel
- Mac
- Ted Healy
- Junior Burns
- Ivan Lebedeff
- Marquis Hugo di Binelli di Pisa
- Isabel Jewell
- A Girl Friend
- Louise Beavers
- Loretta
- Leonard Carey
- Winters
- Mary Forbes
- Mrs. Middleton
- C. Aubrey Smith
- Mr. Middleton
- June Brewster
- Alice Cole
- Tom Kennedy
- Minor Role
- Etta Moten
- Singer
- Gus Arnheim
- Gus Arnheim - Coconut Grove Bandleader
- Hooper Atchley
- Car Salesman
- Ed Brady
- Photographer
- Don Brodie
- Photographer
- James Burke
- First Immigration Officer
- Primo Carnera
- Primo Carnera - in the Opening Montage
- Dorothy DeBorba
- Girl Getting Lola's Autograph at Table
- Billy Dooley
- Man Claiming to Be Lola's Husband
- Ben Erway
- Reporter
- Edward Gargan
- Second Immigration Officer
- Harrison Greene
- Reporter
- Ethel Griffies
- Mrs. Ward - Orphanage Representative
- Gus Arnheim and His Orchestra
- Cocoanut Grove Orchestra
- Grace Hayle
- Mrs. Titcomb
- Tenen Holtz
- White - Lola's Agent
- Kenner G. Kemp
- Nightclub Patron
- Donald Kerr
- Monte - Lola's Makeup Man
- Wilbur Mack
- Van Randolph - Hugo's Lawyer
- Philo McCullough
- Reporter
- Greta Meyer
- Lola's Masseuse
- Miki Morita
- Yokahama
- Philip Morris
- Studio Workman
- Louis Natheaux
- Car Salesman
- William Newell
- Lola's Chauffeur
- Dennis O'Keefe
- Nightclub Patron
- Paul Power
- Cocoanut Grove Patron
- Shirley Ross
- Singer
- Leonard Sillman
- Undetermined Role
- Martha Sleeper
- Lola's Hair Stylist
- Minerva Urecal
- Autograph Seeker
- Dale Van Sickel
- Cocoanut Grove Patron
- Morgan Wallace
- H.E. Gillette
- Kathrin Clare Ward
- Older Orphanage Nurse
- Ruth Warren
- Miss Carroll from Photoplay Magazine
- Allen Wood
- Frankie
