Claire Forlani was born in the United Kingdom and grew up in London. Educated at Arts Educational School, she moved to the United States with her parents Pier Luigi and Barbara Forlani when she was 19 and began starring in films.

Claire has had leading roles in such films as Meet Joe Black (1998), Basquiat (1996), The Rock (1996), Mystery Men (1999), Mallrats (1995), Antitrust (2001), Boys and Girls (2000), The Medallion, Hallam Foe (2007), Flashbacks of a Fool (2008) and Green Street (2005).

Claire is now starring in the Sky International show Domina, about ancient Rome .She appeared with Christopher Plummer in the television series Departure . Other television appearances include STARZ original series Camelot (2011) playing Queen Igraine, The Pentagon Papers (2003), Nightmares & Dreamscapes: From the Stories of Stephen King (2006), and she has had recurring roles on NCIS: Los Angeles (2009) and CSI: NY (2004).

Claire has also appeared in campaigns for Dewars, L'Oréal, Banana Republic, Shiesido and Dior.

She is married to actor Dougray Scott in 2007 and welcomed their son Milo Thomas Scott born 12.27.14