Collin Schiffli was born and raised in Fort Wayne, Indiana. From an early age, he developed a passion for drawing, painting, music and visual storytelling. Collin graduated with a Bachelor of Arts in Film Directing from Columbia College in Chicago and has worked in Los Angles along with screenwriter and brother, Brandon Schiffli, for over a decade.

In 2014, Collin's feature film debut, Animals, won a special grand jury award at the 2014 SXSW Film Festival and was awarded best feature, best director and best actor at The Midwest Independent Film Festival's BMAs in Chicago. Animals also took home top prizes at the Virginia Film Festival and Chicago Critics Film Festival.

His follow up feature, All Creatures Here Below, was distributed by Samuel Goldwyn Films and received a New York Times Critic's Pick, as well as rave reviews from the Los Angeles Times. It resides at 71% on Rotten Tomatoes, despite its polarizing subject matter.

Lionsgate acquired North American rights to Collin's third film, Die In A Gunfight in 2021. The film is a departure in tone from his previous work, but continues to explore the themes of love and hope in a lavish and stylized manner.