Erwin Chargaff was an Austrian–Hungarian biochemist who served as a professor of biochemistry at ‘Columbia University.’ He is primarily known for his work on what is now known as Chargaff’s Rules, which formed the basis of the discovery of the double-helix structure of DNA. Erwin initially worked at ‘Yale University’ but then moved to the ‘University of Berlin.’ During the ‘Nazi’ rule, he moved to Paris for a while, before migrating to New York. He took up a job as a biochemist at ‘Columbia University’ and later became a professor. He retired as a professor emeritus. He felt cheated when James D. Watson, Francis Crick, and Maurice Wilkins won the 1962 ‘Nobel Prize’ for their work on the double-helix pattern of DNA, as he believed his research had formed the basis of their work. Though he spoke against molecular biology and also voluntarily withdrew from active research later, he won many honors and awards. He died in New York, at the age of 96.