Mia Gypsy Mello da Silva Goth, was born October 25, 1993 in Southwark, London, England to a Brazilian mother and a Canadian father.

Aged 14, she was discovered at the Underage Festival in London by fashion photographer Gemma Booth, who signed her to Storm Model Management. She subsequently appeared in advertisements for Vogue and Miu Miu. She began to audition for films at the age of 16, and after finishing sixth form, she won her first role in Lars von Trier's Nymphomaniac and played alongside Willem Dafoe. She later played Sophie Campbell in the Sky Atlantic's crime drama series The Tunnel and appeared in Stephen Fingleton's directed introductory short film Magpie. In 2015, Goth played the lead role of Milja in the post-apocalyptic thriller The Survivalist. She also appeared in the BBC One's crime series Wallander. Goth starred in the disaster adventure-thriller film Everest, which was directed by Baltasar Kormákur. In 2017, Goth played a lead role in the horror film A Cure for Wellness, directed by Gore Verbinski.

In 2018, Goth had a supporting role in Luca Guadagnino's remake of Suspiria, alongside Dakota Johnson and Tilda Swinton, as well as the sci-fi mystery film High Life, directed by French auteur director Claire Denis, opposite Robert Pattinson and Juliette Binoche.