Thomas William Hiddleston was born in Westminster, London, to English-born Diana Patricia (Servaes) and Scottish-born James Norman Hiddleston. His mother is a former stage manager, and his father, a scientist, was the managing director of a pharmaceutical company. He started off at the preparatory school, The Dragon School in Oxford, and by the time he was 13, he boarded at Eton College, at the same time that his parents were going through a divorce. He continued on to the University of Cambridge, where he earned a double first in Classics. He continued to study acting at the Royal Academy of Dramatic Art, from which he graduated in 2005.

Whilst at University of Cambridge, he was seen by the Hamilton Hodell agency in the play "A Streetcar Named Desire" and was signed. Following this, he was cast in his first television role in The Life and Adventures of Nicholas Nickleby (2001). Hiddleston won his first film role as Oakley in Joanna Hogg's award-winning first feature, Unrelated (2007). His breakthrough role came when he portrayed the nemesis Loki in the Marvel Cinematic Universe feature film Thor (2011). He reprised the character in The Avengers (2012), Thor: The Dark World (2013), Thor: Ragnarok (2017), and Avengers: Infinity War (2018).

He has also appeared in Steven Spielberg's War Horse (2011), The Deep Blue Sea (2011), Woody Allen's romantic comedy Midnight in Paris (2011), and the romantic vampire film Only Lovers Left Alive (2013). On television, he appeared on the BBC series The Hollow Crown (2012), in the adaptations of Shakespeare's "Henry IV" and "Henry V". In theatre, he has been in the productions of "Cymbeline" (2007) and "Ivanov" (2008). In December 2013, he starred as the title character in the Donmar Warehouse production of "Coriolanus" which played until February 2014. He won the Laurence Olivier Award for Best Newcomer in a Play for his role in "Cymbeline" while also being nominated for the same award the same year for his role as Cassio in "Othello".