Lenny von Dohlen was born in Augusta, Georgia. As a child, he wished to become a jockey, but grew too tall for his dream. He graduated from the University of Texas/Austin and majored in drama at Loretto Heights College.
His film debut was in the Academy Award-winning Tender Mercies (1983), starring Robert Duvall, written by Horton Foote and directed by Bruce Beresford. From that performance, he was given the leading role in MGM/UA's Electric Dreams (1984). Other starring roles quickly followed: Under the Biltmore Clock (1984), Blind Vision (1992), Jennifer Eight (1992), Edward Zwick's Leaving Normal (1992), David Lynch's Twin Peaks: Fire Walk with Me (1992), and the title role in Billy Galvin (1986), opposite Karl Malden.
In a career known for depth, diversity and mostly dramatic roles, Lenny Von Dohlen shook things up hilariously when he played one of the bumbling bad guys in Twentieth Century Fox's Home Alone 3 (1997). This came on the heels of a string of amazingly complex roles in highly regarded independent films such as Tollbooth (1994), Bird of Prey (1995), One Good Turn (1996), Entertaining Angels (1998), Cadillac (1997) and Frontline (1994).
Von Dohlen made an auspicious television debut in the Emmy Award-winning Kent State: The Day the War Came Home (2000), and has appeared in some of television's most highly regarded shows, such as Thirtysomething (1987), Picket Fences (1992), Chicago Hope (1994), The Lazarus Man (1996), The Pretender (1996), CSI: Miami (2002) and "ABC Afternoon Specials" (1972) {Don't Touch}_ , directed by Beau Bridges. However, he is probably best known for having created the agoraphobic orchid-growing "Harold Smith" in David Lynch's cutting-edge series Twin Peaks (1990). Most recently, he appeared in Masterpiece Theatre's presentation of Eudora Welty's "The Ponder Heart" on PBS. Above all, the theater is his first love. In New York, he created roles in "Asian Shade", "The Team", "Twister" and "Vanishing Act" and "The Maderati", both by Richard Greenberg. For nine months, he starred in Carol Churchill's hit play "Cloud 9", directed by Tommy Tune, followed by The Roundabout Theatre Company's revival of "Desire Under The Elms", opposite Kathy Baker. He has starred in "Hamlet", "Romeo and Juliet", Joe Orton's "Loot", Wedekind's and Lanford Wilson's one-man play "A Poster of the Cosmos". On the West Coast, Mr. Von Dohlen has been see in Wedekind's "Lulu" at the La Jolla Playhouse, "The Blue Room" at the Pasadena Playhouse, in "Theater Distric" at the Black Dahlia Theater, and at the Theater & Boston Court played "Voltaire" in the much acclaimed World Premier of Jean Claude van Italie's "Light" garnering the Los Angeles Critics Circle and Ovation Best Actor Award nominations. Von Dohlen resided in New York and Los Angeles.
On 2022, von Dohlen died after struggling against an undisclosed long illness. He was 63.
