Jacqueline Karstens arrives to do her time on the day Leila de Wit is let go. Makoemba is pregnant, and claims to have been raped by a member of staff. Tessa Boonstra stabs consultant René Wouters with a pair of scissors.
Makoemba has attempted to break out and fallen to her death. But it seems she had help escaping. Inspector de Zwart begins questioning the staff that very night. Teun's girlfriend Anna tells her she's going to marry a man.
Two new inmates arrive: Turkish Derya Usta and the elderly Jante Kruimel. Jacqueline requests permission to go see her personal dentist. Van Beusekom's blood is tested in connection with Makoemba's pregnancy.
Van Beusekom has been arrested and worries about his wife, who has a weak heart. Reporter Froukje Lok joins the inmates for a week to write an article. Derya refuses to let René Wouters visit her children.
Jacqueline is back in jail, and immediately gets into a fight with Teun during dinner. Eefje Winkel and Carla van Beusekom are both falling for Maurits Troost. Froukje Lok uncovers new facts about Makoemba's death.
Josje learns her lover has escaped from jail. Van Beusekom is found innocent, but Inspector de Zwart wants him to play along so he can catch the real culprit. Tessa steals an expensive blouse belonging to Jacqueline's and sneaks into Teun's cell to spend the night with her. Lea's stepdaughter Lieke is caught with XTC pills. Truus is smuggling dope for Latali.
Pregnant Liesbeth Vrijman joins the female prisoners. Tessa is visited by her father. Truus has been hospitalized after an accident and is replaced by a new warden: Regina Jongschaap. Eefje can't keep her hands off Troost.
Regina catches Troost and Eefje being intimate. Van Beusekom resumes his work. Transsexual Marjan Daal joins the group. Jantje is finally allowed a conjugal visit from Ferdinand, but learns something disappointing.
Lea's stepdaughter Lieke visits Dr. de Groot after getting pregnant at a wild House Party. Snorrie is nervous before going on leave for the weekend. Derya is also going on leave, but in she is secretly working with the police to identify her husband's killer. Jantje is collecting sleeping pills. Liesbeth knows that Troost has got Eefje some hash. Troost tells Carla on her birthday that he's in love with Eefje.
Smorrie finds it difficult to be back in jail after a weekend leave. Lea Zandbergen learns that Lieke is has an illness on top of her pregnancy. Liesbeth is agitating everybody. Jantje takes an overdose sleeping pills.
A new inmate, Julia Claus, refuses to disclose why she's being punished. Maurits and Eefje 'get stuck' in the elevator. Josje hears from Froukje, and Anna seeks contact with Teun again. Tonnie agrees to go out with Wiebe.
Leila is glad to be back in jail. Tessa is taken to an institution. Oerlemans has had enough of his wife's adultery. The women organize a going away party for warden Winnie, who is going to emigrate with her husband.
Two male prisoners have somehow acquired weapons and burst into the women's wing during Winnie's going away party. All the women and some of the wardens are held hostage while police try to negotiate from the outside.
New warden Mathilde Beentjes catches Eefje smoking a joint. Angela Brown joins the women in the ward. Wiebe and Tonny grow closer together. Marjan Daal is depressed. Julia's mother visits and wants to come sing for the prisoners.
Liesbeth goes into labor. Jantje tries to escape from the hospital. Wiebe Oerlemans leaves his wife, who destroys his stamp collection in spite. Josje's boyfriend Ger comes to visit. Leila and Teun are disciplined because Leila put shrimps in a set of cushions that ended up in with the prison staff. The women are preparing to celebrate Easter, but the director threatens to cancel the party in case a missing kitchen knife isn't returned.
Eefje learns her mother has passed and acts like she doesn't care. Director Lea Zandbergen is under investigation. Even new warden David Molenaar is questioned on his first day. Jacqueline has had enough of her surroundings.
Lea Zandbergen has been suspended and replaced by Lex Knoop. All the women adore Liesbeth's newborn baby, but Liesbeth's distrust of Julia leads to a fight. When Knoop orders Julia away, the others decide to strike.
Following the prisoner's sit-down protest, the wardens all decide to sign a petition for the return of Lea Zandbergen. Leila has a Polish pen-pal from another prison. Oerlemans implores Troost to stop fooling around with Eefje.
Dr. de Groot looks into Jacqueline's skin problem. Julia Claus and Jante Kruimel return to the women's wing. Josje's case is being reopened. Smorrie learns her husband has been unfaithful just before going on leave.
Smorrie angrily goes home for the weekend. Leila requests to visit her pen pal in another prison. Lea Zandbergen goes out for a drink alone. Dr. de Groot doesn't tell Jacqueline how bad her blood examination results are.
Leila has found Jacqueline's diagnosis. Soon rumors are spreading all over the women's wing. Dr. de Groot still can't bring himself to tell her. Lea Zandbergen has Troost suspended after catching him kissing Eefje.
Regina tells Dr. de Groot that everybody knows that Jacqueline is HIV positive, except Jacqueline herself. But he insists on waiting for more results. Liesbeth is transferred to another floor. Eefje goes on leave for the first time. Josje marries Ger with Lea Zandbergen officiating. Afterwards, Derya is nowhere to be found.